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3.4.13.5: Xaa-methyl-His dipeptidase

This is an abbreviated version!
For detailed information about Xaa-methyl-His dipeptidase, go to the full flat file.

Word Map on EC 3.4.13.5

Reaction

Hydrolysis of anserine (beta-alanyl-/-Npi-methyl-L-histidine), carnosine, homocarnosine, glycyl-/-leucine and other dipeptides with broad specificity. =

Synonyms

acetylhistidine deacetylase, aminoacyl-methylhistidine dipeptidase, aminoacyl-pros-methyl-L-histidine hydrolase, anserinase, ANSN, deacetylase, acetylhistidine, dipeptidase, aminoacylmethylhistidine, EC 3.4.3.4, EC 3.5.1.34, NacHDE, Nalpha-acetylhistidine deacetylase, X-methyl-His dipeptidase, Xaa-methyl-His dipeptidase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.13 Dipeptidases
                3.4.13.5 Xaa-methyl-His dipeptidase

pH Range

pH Range on EC 3.4.13.5 - Xaa-methyl-His dipeptidase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 9
-
less than 10% of maximal activity at pH 5.0 and 9.0
5.2 - 8.5
-
50% of maximal activity at pH 5.2 and at pH 8.5
6 - 8
-
pH 6.0: about 35% of maximal activity, pH 8.0: about 55% of maximal activity
6.5 - 7.8
-
activity is sharply reduced below pH 6.5 and above pH 7.8