3.4.11.15: aminopeptidase Y

This is an abbreviated version!
For detailed information about aminopeptidase Y, go to the full flat file.

Reaction

preferentially, release of N-terminal lysine =

Synonyms

AAP, aminopeptidase (cobalt-activated), aminopeptidase Co, APE3, LapB, lysine aminopeptidase, PF1861, PH1821, PhTET3, TET3, yylAPE

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.11 Aminopeptidases

                3.4.11.15 aminopeptidase Y

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
3	Activating Compound
256	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
2	Crystallization (Commentary)
2	Expression
1	General Information
2	General Stability
1	IC50 Value
48	Inhibitors
5	kcat/KM [mM/s]
7	KM Value [mM]
8	Localization
17	Metals/Ions
14	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
18	Organism
3	PDB ID
9	pH Optimum
2	pH Range
1	pH Stability
1	pI Value
5	Posttranslational Modification
1	Protein Variants
6	Purification (Commentary)
1	Reaction
1	Reaction Type
18	Reference
6	Specific Activity [micromol/min/mg]
65	Substrates and Products (Substrate)
10	Subunits
15	Synonyms
6	Temperature Optimum [°C]
1	Temperature Range [°C]
5	Temperature Stability [°C]
5	Turnover Number [1/s]

Engineering

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Engineering on EC 3.4.11.15 - aminopeptidase Y

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Protein Variants Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

additional information

Legionella pneumophila

-

LapB mutant NU322 (defective for lapB gene) shows a complete loss of lysine aminopeptidase activity and a partial reduction in arginine aminopeptidase activity. When an intact copy of lapB is reintroduced into NU322 aminopeptidase activity is restored

683084