3.2.2.B5: 8-oxoguanine DNA glycosylase
This is an abbreviated version!
For detailed information about 8-oxoguanine DNA glycosylase, go to the full flat file.
Word Map on EC 3.2.2.B5
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3.2.2.B5
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endonuclease
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ser326cys
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mtdna
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glycosylases
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8-ohdg
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7,8-dihydro-8-oxoguanine
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comet
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ape1
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8-oxo-7,8-dihydroguanine
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xrcc1
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8-hydroxy-2'-deoxyguanosine
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formamidopyrimidine
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base-excision
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cross-complementing
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excises
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abasic
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8-hydroxyguanine
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8-oxoguanine-dna
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8-oxo-dg
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mutyh
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8-hydroxydeoxyguanosine
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arg399gln
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asp148glu
- 3.2.2.B5
- endonuclease
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ser326cys
- mtdna
- glycosylases
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8-ohdg
- 7,8-dihydro-8-oxoguanine
- comet
- ape1
- 8-oxo-7,8-dihydroguanine
- xrcc1
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8-hydroxy-2'-deoxyguanosine
- formamidopyrimidine
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base-excision
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cross-complementing
-
excises
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abasic
- 8-hydroxyguanine
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8-oxoguanine-dna
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8-oxo-dg
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mutyh
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8-hydroxydeoxyguanosine
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arg399gln
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asp148glu
Reaction
Synonyms
8-oxoG DNA glycosylase, 8-oxoguanine DNA glycosylase, Af0371, Afogg enzyme, archaeal GO glycosylase, GO-glycosylase, MJ0724, MjaOgg2, mjOgg, ogg, Ogg2, oxoG DNA glycosylase, Pa-AGOG, Pa-AGOG DNA glycosylase, PAE2237, SSO0904, TVG_RS00315
ECTree
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General Information
General Information on EC 3.2.2.B5 - 8-oxoguanine DNA glycosylase
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physiological function
physiological function
the enzyme that is part of the base excision repair (BER) pathway. It protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine, from single- and double-stranded DNA substrates. Bifunctional enzyme that catalyzes the excision of 8-oxoguanine by cleaving the N-glycosylic bond between the base and the deoxyribose moiety (glycosylase activity) and subsequently cleave the DNA backbone (lyase activity, EC 4.2.99.18)
physiological function
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the enzyme that is part of the base excision repair (BER) pathway. It protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine, from single- and double-stranded DNA substrates. Bifunctional enzyme that catalyzes the excision of 8-oxoguanine by cleaving the N-glycosylic bond between the base and the deoxyribose moiety (glycosylase activity) and subsequently cleave the DNA backbone (lyase activity, EC 4.2.99.18)
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