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3.2.2.B5: 8-oxoguanine DNA glycosylase

This is an abbreviated version!
For detailed information about 8-oxoguanine DNA glycosylase, go to the full flat file.

Word Map on EC 3.2.2.B5

Reaction

DNA containing 8-oxoguanine
+
H2O
=
DNA with an abasic site
+
8-oxoguanine

Synonyms

8-oxoG DNA glycosylase, 8-oxoguanine DNA glycosylase, Af0371, Afogg enzyme, archaeal GO glycosylase, GO-glycosylase, MJ0724, MjaOgg2, mjOgg, ogg, Ogg2, oxoG DNA glycosylase, Pa-AGOG, Pa-AGOG DNA glycosylase, PAE2237, SSO0904, TVG_RS00315

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.B5 8-oxoguanine DNA glycosylase

pH Range

pH Range on EC 3.2.2.B5 - 8-oxoguanine DNA glycosylase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.3 - 9.5
pH 7.3: about 50% of maximal activity, pH 9.5: about 45% of maximal ativity, glycosylase/lyase activity is very similar to that of the glycosylase activity alone
7.5 - 10
pH 7.5: about 50% of maximal activity, pH 10.0: about 50% of maximal activity