3.2.2.2: inosine nucleosidase
This is an abbreviated version!
For detailed information about inosine nucleosidase, go to the full flat file.
Word Map on EC 3.2.2.2
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3.2.2.2
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trypanosoma
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vivax
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salvage
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n-glycosidic
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hypoxanthine
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iminoribitols
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trypanocidal
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riboside
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isozyme-specific
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trypanosomiasis
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ribonucleosides
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anthracis
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xanthosine
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fasciculata
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crithidia
- 3.2.2.2
- trypanosoma
- vivax
-
salvage
-
n-glycosidic
- hypoxanthine
- iminoribitols
-
trypanocidal
- riboside
-
isozyme-specific
-
trypanosomiasis
- ribonucleosides
- anthracis
- xanthosine
- fasciculata
-
crithidia
Reaction
Synonyms
guanosine-inosine-preferring nucleoside N-ribohydrolase, inosinase, inosine hydrolase, inosine-adenosine-guanosine nucleoside hydrolase, inosine-guanosine nucleosidase, NSH2, nucleosidase, inosine, purine-specific nucleoside hydrolase
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Engineering
Engineering on EC 3.2.2.2 - inosine nucleosidase
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additional information
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mutants expressing the Arabidopsis thaliana enzyme or the homologue from Oryza sativa exhibit resistance toward toxic fluorouridine, fluorouracil, and fluoroorotic acid. Mutants with increased and decreased nucleosidase activity are delayed in germination
additional information
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mutant strains lacking the basal layer protein exsY and devoid of exosporium lack detectable levels of collagen-like glycoprotein BclA and the basal layer proteins BxpB, BxpC, CotY, and inosine-uridine-preferring nucleoside hydrolase. The mutation does not affect spore production and germination efficiencies or spore resistance but does influence the course of spore outgrow