3.10.1.1: N-sulfoglucosamine sulfohydrolase

This is an abbreviated version!
For detailed information about N-sulfoglucosamine sulfohydrolase, go to the full flat file.

Word Map on EC 3.10.1.1

3.10.1.1

mucopolysaccharidosis

lysosomal

sanfilippo

mps-iiia

naglu

n-sulfate

sulfate-derived

heparinum

medicine

oestrone

hgsnat

sumf1

iduronate

sulfatases

ubiquitin-positive

drug development

pharmacology

diagnostics

Reaction

Synonyms

2-desoxy-2-sulphamido-D-glucose sulphamidase, 2-desoxy-D-glucoside-2-sulphamate sulphohydrolase, heparan N-sulfatase, heparan-N-sulfatase, heparan-N-sulphatase, heparin sulfamidase, N-sulfoglucosamine sulfohydrolase, N-sulphoglucosamine, SGSH, sulfamate sulfohydrolase, sulfamidase, sulfoglucosamine sulfamidase, sulphamate sulphohydrolase, sulphamidase, sulphohydrolase

ECTree

3 Hydrolases

3.10 Acting on sulfur-nitrogen bonds

3.10.1 Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)

3.10.1.1 N-sulfoglucosamine sulfohydrolase

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Results	in table
1	Activating Compound
69	AA Sequence
14	Application
1	CAS Registry Number
9	Cloned(Commentary)
1	Crystallization (Commentary)
608	Disease/ Diagnostics
11	General Information
2	IC50 Value
10	Inhibitors
8	KM Value [mM]
9	Localization
2	Metals/Ions
14	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
181	Organism
4	Pathway
10	PDB ID
12	pH Optimum
3	pH Range
2	pH Stability
1	pI Value
5	Posttranslational Modification
12	Protein Variants
11	Purification (Commentary)
2	Reaction
1	Reaction Type
42	Reference
27	Source Tissue
1	Storage Stability
40	Substrates and Products (Substrate)
6	Subunits
42	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Purification

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Purification on EC 3.10.1.1 - N-sulfoglucosamine sulfohydrolase

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apparent homogeneity

partial purification

purification of recombinant enzyme

recombinant

recombinant C-terminally His6-tagged full-length enzyme from HEK-293 cells by nickel affinity croomatography

Homo sapiens

P51688

733005

SP-Sepharose column chromatography and Sephacryl S-300 gel filtration

Homo sapiens

P51688

700315