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3.1.7.2: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase

This is an abbreviated version!
For detailed information about guanosine-3',5'-bis(diphosphate) 3'-diphosphatase, go to the full flat file.

Word Map on EC 3.1.7.2

Reaction

guanosine 3',5'-bis(diphosphate)
+
H2O
=
GDP
+
diphosphate

Synonyms

(p)ppGpp synthetase/hydrolase, (ppGpp)ase, 3',5'-bis(diphosphate) 3'-pyrophosphate hydrolase, guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase, guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase, HDDC3, MESH1, metazoan SpoT homolog-1, penta-phosphate guanosine-3'-diphosphohydrolase, penta-phosphate guanosine-3'-pyrophosphohydrolase, ppGpp hydrolase, ppGpp phosphohydrolase, ppGpp-3'-pyrophosphohydrolase, pyrophosphatase, guanosine 3',5'-bis(diphosphate) 3'-, RelSeq

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.7 Diphosphoric-monoester hydrolases
                3.1.7.2 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase

Natural Substrates Products

Natural Substrates Products on EC 3.1.7.2 - guanosine-3',5'-bis(diphosphate) 3'-diphosphatase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ppGpp + H2O
Gpp + diphosphate
show the reaction diagram
ppGpp + H2O
ppG + diphosphate
show the reaction diagram
additional information
?
-
-
only ppGpp, and no other nucleotide, is effectively hydrolyzed by human MESH1
-
-
?