3.1.26.7: ribonuclease P4
This is an abbreviated version!
For detailed information about ribonuclease P4, go to the full flat file.
Reaction
endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor =
Synonyms
P4, ribonuclease P ribozyme, ribonuclease P RNA, RNase P, RNase P RNA, RNaseP P4
ECTree
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Substrates Products
Substrates Products on EC 3.1.26.7 - ribonuclease P4
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REACTION DIAGRAM
tRNA + pre-part nucleotides
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involved in the hydrolysis of phosphodiester bonds in precursors of transfer RNA (pre-tRNA) to form mature tRNA
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-
?
pre-tRNA + H2O
tRNA + pre-part nucleotides
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the helix P4 is important in the ribozyme for positioning divalent metal ions that are required for catalysis
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-
?
pre-tRNA + H2O
tRNA + pre-part nucleotides
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structure-function relationship, moving the bulged nucleotides proximal to sites of metal ion coordination in helix P4 is important for catalysis, overview
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-
?
tRNA precursor + H2O
tRNA + 5'-terminal oligonucleotide
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5'-end sequence is pGGUGGGG
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-
?
tRNA precursor + H2O
tRNA + 5'-terminal oligonucleotide
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processing of the transcript of the synthetic tyrosine suppressor tRNA gene
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-
?
tRNA precursor + H2O
tRNA + 5'-terminal oligonucleotide
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-
-
-
?
tRNA precursor + H2O
tRNA + 5'-terminal oligonucleotide
-
processing of the transcript of the synthetic tyrosine suppressor tRNA gene
-
-
?