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3.1.13.B1: 5'-3' exoribonuclease

This is an abbreviated version!
For detailed information about 5'-3' exoribonuclease, go to the full flat file.

Word Map on EC 3.1.13.B1

Reaction

exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates =

Synonyms

5'-3' exoribonuclease 2, 5'-to-3' exoribonuclease, Pab-RNase J, PAB1751, Rat1, Saci-aCPSF2, Saci2362, Sso-RNase J, SSO0386, Tk-RNase J, Tk1469

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.13 Exoribonucleases producing 5′-phosphomonoesters
                3.1.13.B1 5'-3' exoribonuclease

Activating Compound

Activating Compound on EC 3.1.13.B1 - 5'-3' exoribonuclease

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ATP
ATP significantly enhances Rat1/Rai1-mediated RNAPII termination. The ATP-dependent effect seems to be unique to Rat1/Rai1. ATP addition does not stimulate the processivity of Rat1. Rather, it slightly reduces the exonuclease activity because 1 mM of ATP is sufficient to chelate the Mg2+ ion necessary for the nuclease activity of Rat1, suggesting that ATP affects Rat1-mediated termination in a somewhat different manner
additional information
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