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3.1.13.B1: 5'-3' exoribonuclease

This is an abbreviated version!
For detailed information about 5'-3' exoribonuclease, go to the full flat file.

Word Map on EC 3.1.13.B1

Reaction

exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates =

Synonyms

5'-3' exoribonuclease 2, 5'-to-3' exoribonuclease, Pab-RNase J, PAB1751, Rat1, Saci-aCPSF2, Saci2362, Sso-RNase J, SSO0386, Tk-RNase J, Tk1469

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.13 Exoribonucleases producing 5′-phosphomonoesters
                3.1.13.B1 5'-3' exoribonuclease

Inhibitors

Inhibitors on EC 3.1.13.B1 - 5'-3' exoribonuclease

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
20 mM, strong inhibition
initiation factor a/eIF2(gamma)
binding of translation initiation factor a/eIF2(gamma) to the 5'-end of mRNA counteracts the 5'-to-3' exoribonucleolytic activity in vitro. The factor binds by virtue of the gamma-subunit to the 5'-end of tri-phosphorylated mRNAs and thereby increases the stability of the 5'-part of mRNAs
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