3.1.11.7: adenosine-5'-diphospho-5'-[DNA] diphosphatase
This is an abbreviated version!
For detailed information about adenosine-5'-diphospho-5'-[DNA] diphosphatase, go to the full flat file.
Word Map on EC 3.1.11.7
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3.1.11.7
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apraxia
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oculomotor
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single-strand
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ocular
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cerebellar
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early-onset
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hypoalbuminemia
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polynucleotide
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5'-adenylated
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xrcc4
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friedreich
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ataxia-oculomotor
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fen1
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forkhead-associated
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deadenylation
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medicine
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cross-complementing
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3'-phosphoglycolate
- 3.1.11.7
- apraxia
-
oculomotor
-
single-strand
-
ocular
- cerebellar
-
early-onset
- hypoalbuminemia
- polynucleotide
-
5'-adenylated
- xrcc4
- friedreich
-
ataxia-oculomotor
- fen1
-
forkhead-associated
-
deadenylation
- medicine
-
cross-complementing
-
3'-phosphoglycolate
transferred to EC 3.6.1.71
Synonyms
Synonyms
aprataxin, APTX, DNA-adenylate hydrolase, HNT3, RNA-DNA deadenylase
ECTree
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Reference
Reference on EC 3.1.11.7 - adenosine-5'-diphospho-5'-[DNA] diphosphatase
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Hanaoka, K.; Tanaka, W.; Kayanuma, M.; Shoji, M.
A QM/MM study of the 5'-AMP DNA hydrolysis of aprataxin
Chem. Phys. Lett.
631-632
16-20
2015
Homo sapiens (Q7Z2E3)
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Horton, J.K.; Stefanick, D.F.; Caglayan, M.; Zhao, M.L.; Janoshazi, A.K.; Prasad, R.; Gassman, N.R.; Wilson, S.H.
XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity
DNA Repair
64
26-33
2018
Saccharomyces cerevisiae (Q08702), Homo sapiens (Q7Z2E3)
Tumbale, P.; Schellenberg, M.; Mueller, G.; Fairweather, E.; Watson, M.; Little, J.; Krahn, J.; Waddell, I.; London, R.; Williams, R.
Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease
EMBO J.
37
e98875
2018
Homo sapiens (Q7Z2E3)
Garcia-Diaz, B.; Barca, E.; Balreira, A.; Lopez, L.C.; Tadesse, S.; Krishna, S.; Naini, A.; Mariotti, C.; Castellotti, B.; Quinzii, C.M.
Lack of aprataxin impairs mitochondrial functions via downregulation of the APE1/NRF1/NRF2 pathway
Hum. Mol. Genet.
24
4516-4529
2015
Homo sapiens (Q7Z2E3)
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