3.1.11.7: adenosine-5'-diphospho-5'-[DNA] diphosphatase
This is an abbreviated version!
For detailed information about adenosine-5'-diphospho-5'-[DNA] diphosphatase, go to the full flat file.
Word Map on EC 3.1.11.7
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3.1.11.7
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apraxia
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oculomotor
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single-strand
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ocular
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cerebellar
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early-onset
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hypoalbuminemia
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polynucleotide
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5'-adenylated
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xrcc4
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friedreich
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ataxia-oculomotor
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fen1
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forkhead-associated
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deadenylation
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medicine
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cross-complementing
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3'-phosphoglycolate
- 3.1.11.7
- apraxia
-
oculomotor
-
single-strand
-
ocular
- cerebellar
-
early-onset
- hypoalbuminemia
- polynucleotide
-
5'-adenylated
- xrcc4
- friedreich
-
ataxia-oculomotor
- fen1
-
forkhead-associated
-
deadenylation
- medicine
-
cross-complementing
-
3'-phosphoglycolate
transferred to EC 3.6.1.71
Synonyms
Synonyms
aprataxin, APTX, DNA-adenylate hydrolase, HNT3, RNA-DNA deadenylase
ECTree
3.1.11.7 adenosine-5'-diphospho-5'-[DNA] diphosphataseAdvanced search results
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results (Crystallization
Crystallization on EC 3.1.11.7 - adenosine-5'-diphospho-5'-[DNA] diphosphatase
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CRYSTALLIZATION (Commentary) 
ORGANISM
UNIPROT
LITERATURE
purified wild-type enzyme in complex with RNA/DNA, hAPTX-nicked-RNA-DNA-AMP-Zn2+ complex is grown by mixing 300 nl of 10 mg/ml hAptx (165-342) protein and 1 mM AMP, 1.5:1 DNA:protein molar ratio, in 150 mM NaCl, 20 mM Tris-HCl, pH 7.5, and 0.1% 2-mercaptoethanol, with an equal volume of precipitant solution containing 100 mM MES, pH 6.5, 16% w/v PEG 3350 at 4°C, methods for mutant product complexes hAPTX-R199H/RNA-DNA/AMP-Zn2+, hAPTXH201Q/RNA-DNA/AMP-Zn2+, hAPTX-S242N/RNA-DNA/AMPZn2+, hAPTX-L248M/DNA/AMP-Zn2+, and hAPTX-V263G/RNA-DNA/AMP-Zn2+, differ, overview. X-ray diffraction structure determination and analysis, molecular replacement using PDB ID 4NDG as a search model
