2.1.3.15: acetyl-CoA carboxytransferase

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For detailed information about acetyl-CoA carboxytransferase, go to the full flat file.

Word Map on EC 2.1.3.15

2.1.3.15

mycobacterium

tuberculosis

mycolic

acyl-coas

smegmatis

carboxylases

malonyl-coa

propionyl-coa

acyl-coenzyme

methylmalonyl-coa

haloxyfop

isoniazid

accases

Reaction

[biotin carboxyl-carrier protein]-N6-carboxybiotinyl-L-lysine

[biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine

Synonyms

ACC, ACC2, accAD, ACCase, accD5, accD6, Acetyl CoA carboxylase, acetyl-CoA carboxylase, acetyl-CoA carboxylase carboxyltransferase domain, carboxyltransferase, CT-alphabeta subcomplex

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.3 Carboxy- and carbamoyltransferases

2.1.3.15 acetyl-CoA carboxytransferase

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1	Activating Compound
65811	AA Sequence
4	Cloned(Commentary)
2	Cofactor
3	Crystallization (Commentary)
18	Disease/ Diagnostics
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3	Ki Value [mM]
2	KM Value [mM]
1	Localization
14	Natural Substrates/ Products (Substrates)
211	Organism
8	Pathway
6	Purification (Commentary)
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13	Reference
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28	Synonyms
1	Systematic Name

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Systematic Name on EC 2.1.3.15 - acetyl-CoA carboxytransferase

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[biotin carboxyl-carrier protein]-N6-carboxybiotinyl-L-lysine:acetyl-CoA:carboxytransferase

The enzyme catalyses the transfer of a carboxyl group carried on a biotinylated biotin carboxyl carrier protein (BCCP) to acetyl-CoA, forming malonyl-CoA. In some organisms this activity is part of a multi-domain polypeptide that includes the carrier protein and EC 6.3.4.14, biotin carboxylase (see EC 6.4.1.2, acetyl-CoA carboxylase). Some enzymes can also carboxylate propanonyl-CoA and butanoyl-CoA (cf. EC 6.4.1.3, propionyl-CoA carboxylase).