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2.1.3.15: acetyl-CoA carboxytransferase

This is an abbreviated version!
For detailed information about acetyl-CoA carboxytransferase, go to the full flat file.

Word Map on EC 2.1.3.15

Reaction

[biotin carboxyl-carrier protein]-N6-carboxybiotinyl-L-lysine
+
acetyl-CoA
=
[biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine
+
malonyl-CoA

Synonyms

ACC, ACC2, accAD, ACCase, accD5, accD6, Acetyl CoA carboxylase, acetyl-CoA carboxylase, acetyl-CoA carboxylase carboxyltransferase domain, carboxyltransferase, CT-alphabeta subcomplex

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.3 Carboxy- and carbamoyltransferases
                2.1.3.15 acetyl-CoA carboxytransferase

Disease

Disease on EC 2.1.3.15 - acetyl-CoA carboxytransferase

Please use the Disease Search for a specific query.
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Tuberculosis
AccD6, a key carboxyltransferase essential for mycolic acid synthesis in Mycobacterium tuberculosis, is dispensable in a nonpathogenic strain.
AccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosis.
Binding of activated isoniazid with acetyl-CoA carboxylase from Mycobacterium tuberculosis.
Pleiotropic effect of AccD5 and AccE5 depletion in acyl-coenzyme A carboxylase activity and in lipid biosynthesis in mycobacteria.
Structural diversity in the six-fold redundant set of acyl-CoA carboxyltransferases in Mycobacterium tuberculosis.
Structure, activity, and inhibition of the Carboxyltransferase ?-subunit of acetyl coenzyme A carboxylase (AccD6) from Mycobacterium tuberculosis.
Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis.