1.14.19.32: palmitoyl-CoA 14-(E/Z)-desaturase
This is an abbreviated version!
For detailed information about palmitoyl-CoA 14-(E/Z)-desaturase, go to the full flat file.
Reaction
+ 2 ferrocytochrome b5 + + 2 H+ = + 2 ferricytochrome b5 + 2 H2O
Synonyms
DELTA14 desaturase, DELTA14-desaturase
ECTree
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General Information
General Information on EC 1.14.19.32 - palmitoyl-CoA 14-(E/Z)-desaturase
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evolution
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origin and evolution of the DELTA14 desaturase, phylogenetic analysis and tree, detailed overview
metabolism
physiological function
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the enzyme is involved in the synthesis of pheromone compound (Z,E)-9,12-tetradecadienyl acetate from pheromone precursor palmitoyl-CoA
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the enzyme is involved in biosynthesis of (Z)-12- and (E)-12-tetradecenyl acetates
metabolism
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the enzyme is involved in the sex pheromone biosynthetic pathway. Two pathways exist, both initiate from C16:acyl-CoA, with one involving DELTA14 and DELTA9 desaturation to generate Z9,E12-14:acyl, and the other involving the chain shortening of C16:acyl-CoA to C14:acyl-CoA, followed by DELTA12 and DELTA9 desaturation to generate Z9,E12-14:acyl-CoA. Then, a final reduction and acetylation generates Z9,E12-14:OAc, overview. Desaturases introduce a double bond into the fatty acyl carbon chain, with strict regio- and stereo-selectivity