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1.11.1.8: iodide peroxidase

This is an abbreviated version!
For detailed information about iodide peroxidase, go to the full flat file.

Word Map on EC 1.11.1.8

Reaction

2 iodide +

H2O2
+ 2 H+ =
diiodine
 + 2 H2O

Synonyms

bromoperoxidase, high-molecular weight-thyroid peroxidase, HMW-TPO, hrTPO, hTPO, iodide peroxidase-tyrosine iodinase, iodinase, iodoperoxidase (heme type), thyroid peroxidase, thyroperoxidase, TPO, TPOX, TPQ, tyrosine iodinase, vanadium bromoperoxidase, vBPO

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.8 iodide peroxidase

Cloned

Cloned on EC 1.11.1.8 - iodide peroxidase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
CHO-K1 cells introduced with mutated TPO-MRNA
-
expressed in CHO cells
-
expressed in FTC-238 cells
-
expressed in High Five cells, active enzyme
-
expressed in High Five cells, activity similar to native enzyme when grown in presence of delta-aminolevulinic acid, enzyme in supernatant
-
expressed in High Five cells, enzyme insoluble and inactive
-
expressed in insect cells and in Chinese hamster ovary cells, activity detected when grown in presence of hematin or hemin
-
expressed in Sf9 cells, no activity when grown in serum free medium, active when grown in medium containing 10% fetal calf serum and 1 mg/l haematin
-
expression in AD-293 cell
-
expression in baculovirus system
expression in Chinese hamster ovary (CHO) cells
-
expression in CHO and LentiX-293 cell
stable expression of mutant enzymes at the surface of CHO cells
-