1.11.1.8: iodide peroxidase
This is an abbreviated version!
For detailed information about iodide peroxidase, go to the full flat file.
Word Map on EC 1.11.1.8
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1.11.1.8
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thyroglobulin
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tsh
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autoimmune
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hypothyroidism
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autoantibody
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thyroxin
-
women
-
graves
-
tpoabs
-
hashimoto
-
thyrotropin
-
thyroid-stimulating
-
pregnancy
-
subclinical
-
euthyroidism
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triiodothyronine
-
goiter
-
follicular
-
overt
-
thyrocytes
-
anti-tpo
-
antithyroid
-
symporter
-
organification
-
trimester
-
levothyroxine
-
autoantigens
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thyroid-specific
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frtl-5
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guaiacol
-
methimazole
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lactoperoxidase
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radioiodine
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propylthiouracil
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goitrous
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thyrotoxicosis
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antibody-negative
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multinodular
-
analysis
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peroxidase-catalyzed
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hypothalamic-pituitary-thyroid
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ophthalmopathy
-
gadas
-
tsh-induced
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anti-thyroglobulin
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medicine
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thyroid-associated
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tsh-stimulated
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chloroperoxidase
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synthesis
-
nodosum
-
haloperoxidases
-
thyrotoxic
- 1.11.1.8
- thyroglobulin
- tsh
- autoimmune
- hypothyroidism
- autoantibody
- thyroxin
- women
- graves
-
tpoabs
- hashimoto
- thyrotropin
-
thyroid-stimulating
- pregnancy
-
subclinical
-
euthyroidism
- triiodothyronine
- goiter
-
follicular
-
overt
- thyrocytes
-
anti-tpo
-
antithyroid
-
symporter
-
organification
-
trimester
- levothyroxine
- autoantigens
-
thyroid-specific
-
frtl-5
- guaiacol
- methimazole
- lactoperoxidase
-
radioiodine
- propylthiouracil
-
goitrous
- thyrotoxicosis
-
antibody-negative
-
multinodular
- analysis
-
peroxidase-catalyzed
-
hypothalamic-pituitary-thyroid
-
ophthalmopathy
-
gadas
-
tsh-induced
-
anti-thyroglobulin
- medicine
-
thyroid-associated
-
tsh-stimulated
- chloroperoxidase
- synthesis
- nodosum
- haloperoxidases
-
thyrotoxic
Reaction
Synonyms
bromoperoxidase, high-molecular weight-thyroid peroxidase, HMW-TPO, hrTPO, hTPO, iodide peroxidase-tyrosine iodinase, iodinase, iodoperoxidase (heme type), thyroid peroxidase, thyroperoxidase, TPO, TPOX, TPQ, tyrosine iodinase, vanadium bromoperoxidase, vBPO
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General Information
General Information on EC 1.11.1.8 - iodide peroxidase
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metabolism
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the enzyme catalyzes the transfer of iodine to thyroglobulin during thyroid hormone synthesis
physiological function
thyroid peroxidase is the key enzyme involved in thyroid hormone synthesis
physiological function
treatment of animals with inhibitors propylthiouracil or methimazole decreases thyroid hormone triiodothyronine and tetraiodothyronine levels in the thyroid gland and increases thyroid-stimulating hormone level. Less than 30% inhibition of TPO in vitro is sufficient to reduce serum tetraiodothyronine level by 20%