1.1.1.69: gluconate 5-dehydrogenase

This is an abbreviated version, for detailed information about gluconate 5-dehydrogenase, go to the full flat file.

Reaction

D-gluconate
+
NAD(P)+
=
5-Dehydro-D-gluconate
+
NAD(P)H
+
H+

Synonyms

5-keto D-gluconate reductase, 5-keto-D-gluconate 5-reductase, 5-keto-D-gluconate reductase, 5-ketogluconate 5-reductase, 5-ketogluconate reductase, 5KGA reductase, 5KGR, dehydrogenase, gluconate 5-, GA5DH, gluconate 5-dehydrogenase, gluconate-5-dehydrogenase, gluconate:NADP 5-oxidoreductase, GNO, GOX2187 gene product, pyrroloquinoline quinone-dependent gluconate-5-dehydrogenase, QGA-5-DH, reductase, 5-ketogluconate 5-

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.69 gluconate 5-dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.69 - gluconate 5-dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,3-butanediol + NAD+
? + NADH
show the reaction diagram
5-dehydro-D-fructose + NADPH
D-fructose + NADP+
show the reaction diagram
-
23% of the activity with 5-dehydro-D-gluconate
-
-
?
5-dehydro-D-gluconate + NADH
D-gluconate + NAD+
show the reaction diagram
5-dehydro-D-gluconate + NADH + H+
D-gluconate + NAD+
show the reaction diagram
5-dehydro-D-gluconate + NADPH
D-gluconate + NADP+
show the reaction diagram
5-dehydro-D-gluconate + NADPH + H+
D-gluconate + NADP+
show the reaction diagram
5-keto D-gluconate + NADPH
D-gluconate + NADP+
show the reaction diagram
-
-
-
-
?
D-arabitol + NAD+
? + NADH
show the reaction diagram
D-fructose + NADPH
5-dehydro-D-fructose + NADP+
show the reaction diagram
D-gluconate + NAD+
5-dehydro-D-gluconate + NADH + H+
show the reaction diagram
D-gluconate + NADP+
5-dehydro-D-gluconate + NADPH
show the reaction diagram
D-gluconate + NADP+
5-dehydro-D-gluconate + NADPH + H+
show the reaction diagram
D-gluconic acid + NAD+
? + NADH
show the reaction diagram
D-glucono-delta-lactone + NADP+
?
show the reaction diagram
-
14% of the activity with D-gluconate
-
-
?
D-glucose + ?
5-keto-D-gluconic acid + ?
show the reaction diagram
D-mannitol + NAD+
? + NADH
show the reaction diagram
D-sorbitol + NAD+
? + NADH
show the reaction diagram
glycerol + NAD+
? + NADH
show the reaction diagram
138% of activity with D-sorbitol
-
-
?
meso-erytritol + NAD+
? + NADH
show the reaction diagram
143% of activity with D-sorbitol
-
-
?
ribitol + NAD+
? + NADH
show the reaction diagram
66% of activity with D-sorbitol
-
-
?
sorbitol + NAD+
? + NADH
show the reaction diagram
additional information
?
-
-
production of 5-keto D-gluconate from D-gluconate
-
-
-