1.1.1.69: gluconate 5-dehydrogenase

This is an abbreviated version, for detailed information about gluconate 5-dehydrogenase, go to the full flat file.

Reaction

D-gluconate
+
NAD(P)+
=
5-Dehydro-D-gluconate
+
NAD(P)H
+
H+

Synonyms

5-keto D-gluconate reductase, 5-keto-D-gluconate 5-reductase, 5-keto-D-gluconate reductase, 5-ketogluconate 5-reductase, 5-ketogluconate reductase, 5KGA reductase, 5KGR, dehydrogenase, gluconate 5-, GA5DH, gluconate 5-dehydrogenase, gluconate-5-dehydrogenase, gluconate:NADP 5-oxidoreductase, GNO, GOX2187 gene product, pyrroloquinoline quinone-dependent gluconate-5-dehydrogenase, QGA-5-DH, reductase, 5-ketogluconate 5-

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.69 gluconate 5-dehydrogenase

Temperature Stability

Temperature Stability on EC 1.1.1.69 - gluconate 5-dehydrogenase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
40
-
loss of activity after a few min
50
-
pH 7.5, 10 min, stable up to
55
-
5 min, in presence of D-gluconate or 5-dehydro-D-gluconate, even at 0.0001 mg/ml protein
70
-
10 min, pH 7.5, about 75% loss of activity
additional information