1.1.1.144: perillyl-alcohol dehydrogenase

This is an abbreviated version, for detailed information about perillyl-alcohol dehydrogenase, go to the full flat file.

Reaction

perillyl alcohol
+
NAD+
=
perillyl aldehyde
+
NADH
+
H+

Synonyms

ADH, dehydrogenase, perillyl alcohol, perillyl alcohol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.144 perillyl-alcohol dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.144 - perillyl-alcohol dehydrogenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ag+
-
0.005 mM, complete inhibition, prevented by 10 mM glutathione
Cu2+
-
5 mM, complete inhibition, prevented by 5 mM glutathione
Hg2+
-
0.005 mM, complete inhibition, prevented by 10 mM glutathione
iodoacetate
-
10 mM, 95% inhibition, prevented by 10 mM glutathione
NADH
-
competitive inhibition
Ni2+
-
2 mM, 75% inhibition, complete reversion with 5 mM EDTA
o-phenanthroline
-
at concentrations higher than 3 mM and low concentration of NAD+, about 50% inhibition
p-hydroxymercuribenzoate
-
0.005 mM, complete inhibition, prevented by 10 mM glutathione
Zn2+
-
2 mM, 75% inhibition, complete reversion with 10 mM EDTA
additional information
-
glucose represses the induction of the enzyme by limonene
-