Sequence of PIGA_PSEAE
EC Number:1.14.99.58
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
heme oxygenase (biliverdin-IX-beta and delta-forming)
G3XCZ8
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
198
21954
Reaction
protoheme + 3 reduced acceptor + 3 O2 = biliverdin-IX-beta + CO + Fe2+ + 3 acceptor + 3 H2O
Other sequences found for EC No. 1.14.99.58
General information:
Sequence
0 MDTLAPESTR QNLRSQRLNL LTNEPHQRLE SLVKSKEPFA SRDNFARFVA AQYLFQHDLE
60 PLYRNEALAR LFPGLASRAR DDAARADLAD LGHPVPEGDQ SVREADLSLA EALGWLFVSE
120 GSKLGAAFLF KKAAALELDE NFGARHLAEP EGGRAQGWKS FVAILDGIEL NEEEERLAAK
180 GASDAFNRFG DLLERTFA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
458941
Stover C.K.,Pham X.-Q.T.,Erwin A.L.,Mizoguchi S.D.,Warrener P.,Hickey M.J.,Brinkman F.S.L.,Hufnagle W.O.,Kowalik D.J.,Lagrou M.,Garber R.L.,Goltry L.,Tolentino E.,Westbrock-Wadman S.,Yuan Y.,Brody L.L.,Coulter S.N.,Folger K.R.,Kas A.,Larbig K.,Lim R.M.,Smith K.A.,Spencer D.H.,Wong G.K.-S.,Wu Z.,Paulsen I.T.,Reizer J.,Saier M.H. Jr.,Hancock R.E.W.,Lory S.,Olson M.V.
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.
Nature
406
959-964
2000
458942
Ratliff M.,Zhu W.,Deshmukh R.,Wilks A.,Stojiljkovic I.
Homologues of neisserial heme oxygenase in Gram-negative bacteria: degradation of heme by the product of the pigA gene of Pseudomonas aeruginosa.
J. Bacteriol.
183
6394-6403
2001
458943
Caignan G.A.,Deshmukh R.,Wilks A.,Zeng Y.,Huang H.W.,Moenne-Loccoz P.,Bunce R.A.,Eastman M.A.,Rivera M.
Oxidation of heme to beta- and delta-biliverdin by Pseudomonas aeruginosa heme oxygenase as a consequence of an unusual seating of the heme.
J. Am. Chem. Soc.
124
14879-14892
2002
458944
Friedman J.,Lad L.,Li H.,Wilks A.,Poulos T.L.
Structural basis for novel delta-regioselective heme oxygenation in the opportunistic pathogen Pseudomonas aeruginosa.
Biochemistry
43
5239-5245
2004
