Sequence of OAS1_PIG
EC Number:2.7.7.84
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
3 ATP = pppA2'p5'A2'p5'A + 2 diphosphate
Other sequences found for EC No. 2.7.7.84
General information:
Sequence
show sequence in normal format
>Q29599|2'-5' oligoadenylate synthase|EC 2.7.7.84|Sus scrofa|Swiss-Prot
MELRHTPARDLDKFIEDHLLPNTCFRTQVKEAIDIVCRFLKERCFQGTADPVRVSKVVKG
GSSGKGTTLRGRSDADLVVFLTKLTSFEDQLRRRGEFIQEIRRQLEACQREQKFKVTFEV
QSPRRENPRALSFVLSSPQLQQEVEFDVLPAFDALGQWTPGYKPNPEIYVQLIKECKSRG
KEGEFSTCFTELQRDFLRNRPTKLKSLIRLVKHWYQTCKKTHGNKLPPQYALELLTVYAW
EQGSRKTDFSTAQGFQTVLELVLKHQKLCIFWEAYYDFTNPVVGRCMLQQLKKPRPVILD
PADPTGNVGGGDTHSWQRLAQEARVWLGYPCCKNLDGSLVGAWTMLQKI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
453331
Winteroe A.K.,Fredholm M.,Davies W.
Evaluation and characterization of a porcine small intestine cDNA library: analysis of 839 clones.
Mamm. Genome
7
509-517
1996
453332
Torralba S.,Sojat J.,Hartmann R.
2'-5' oligoadenylate synthetase shares active site architecture with the archaeal CCA-adding enzyme.
Cell. Mol. Life Sci.
65
2613-2620
2008
453333
Kristiansen H.,Scherer C.A.,McVean M.,Iadonato S.P.,Vends S.,Thavachelvam K.,Steffensen T.B.,Horan K.A.,Kuri T.,Weber F.,Paludan S.R.,Hartmann R.
Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.
J. Virol.
84
11898-11904
2010
453334
Hartmann R.,Justesen J.,Sarkar S.N.,Sen G.C.,Yee V.C.
Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase.
Mol. Cell
12
1173-1185
2003
