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Sequence of OAS1_PIG

EC Number:2.7.7.84

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2'-5' oligoadenylate synthase
Q29599
Sus scrofa
349
40246
Reaction
3 ATP = pppA2'p5'A2'p5'A + 2 diphosphate
Other sequences found for EC No. 2.7.7.84

General information:

Sequence
show sequence in fasta format
  0 MELRHTPARD LDKFIEDHLL PNTCFRTQVK EAIDIVCRFL KERCFQGTAD PVRVSKVVKG
 60 GSSGKGTTLR GRSDADLVVF LTKLTSFEDQ LRRRGEFIQE IRRQLEACQR EQKFKVTFEV
120 QSPRRENPRA LSFVLSSPQL QQEVEFDVLP AFDALGQWTP GYKPNPEIYV QLIKECKSRG
180 KEGEFSTCFT ELQRDFLRNR PTKLKSLIRL VKHWYQTCKK THGNKLPPQY ALELLTVYAW
240 EQGSRKTDFS TAQGFQTVLE LVLKHQKLCI FWEAYYDFTN PVVGRCMLQQ LKKPRPVILD
300 PADPTGNVGG GDTHSWQRLA QEARVWLGYP CCKNLDGSLV GAWTMLQKI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
453331
Winteroe A.K.,Fredholm M.,Davies W.
Evaluation and characterization of a porcine small intestine cDNA library: analysis of 839 clones.
Mamm. Genome
7
509-517
1996
453332
Torralba S.,Sojat J.,Hartmann R.
2'-5' oligoadenylate synthetase shares active site architecture with the archaeal CCA-adding enzyme.
Cell. Mol. Life Sci.
65
2613-2620
2008
453333
Kristiansen H.,Scherer C.A.,McVean M.,Iadonato S.P.,Vends S.,Thavachelvam K.,Steffensen T.B.,Horan K.A.,Kuri T.,Weber F.,Paludan S.R.,Hartmann R.
Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.
J. Virol.
84
11898-11904
2010
453334
Hartmann R.,Justesen J.,Sarkar S.N.,Sen G.C.,Yee V.C.
Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase.
Mol. Cell
12
1173-1185
2003