Sequence of HACA_METJA
EC Number:4.2.1.114
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
methanogen homoaconitase
Q58409
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
420
46063
Reaction
(R)-2-hydroxybutane-1,2,4-tricarboxylate = (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate
Other sequences found for EC No. 4.2.1.114
General information:
Sequence
show sequence in normal format
>Q58409|methanogen homoaconitase|EC 4.2.1.114|Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)|Swiss-Prot
MTLVEKILSKKVGYEVCAGDSIEVEVDLAMTHDGTTPLAYKALKEMSDSVWNPDKIVVAF
DHNVPPNTVKAAEMQKLALEFVKRFGIKNFHKGGEGICHQILAENYVLPNMFVAGGDSHT
CTHGAFGAFATGFGATDMAYIYATGETWIKVPKTIRVDIVGKNENVSAKDIVLRVCKEIG
RRGATYMAIEYGGEVVKNMDMDGRLTLCNMAIEMGGKTGVIEADEITYDYLKKERGLSDE
DIAKLKKERITVNRDEANYYKEIEIDITDMEEQVAVPHHPDNVKPISDVEGTEINQVFIG
SCTNGRLSDLREAAKYLKGREVHKDVKLIVIPASKKVFLQALKEGIIDIFVKAGAMICTP
GCGPCLGAHQGVLAEGEICLSTTNRNFKGRMGHINSYIYLASPKIAAISAVKGYITNKLD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
41754
Bult C.J.,White O.,Olsen G.J.,Zhou L.,Fleischmann R.D.,Sutton G.G.,Blake J.A.,FitzGerald L.M.,Clayton R.A.,Gocayne J.D.,Kerlavage A.R.,Dougherty B.A.,Tomb J.-F.,Adams M.D.,Reich C.I.,Overbeek R.,Kirkness E.F.,Weinstock K.G.,Merrick J.M.,Glodek A.,Scott J.L.,Geoghagen N.S.M.,Weidman J.F.,Fuhrmann J.L.,Nguyen D.,Utterback T.R.,Kelley J.M.,Peterson J.D.,Sadow P.W.,Hanna M.C.,Cotton M.D.,Roberts K.M.,Hurst M.A.,Kaine B.P.,Borodovsky M.,Klenk H.-P.,Fraser C.M.,Smith H.O.,Woese C.R.,Venter J.C.
Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.
Science
273
1058-1073
1996
41755
Drevland R.M.,Waheed A.,Graham D.E.
Enzymology and evolution of the pyruvate pathway to 2-oxobutyrate in Methanocaldococcus jannaschii.
J. Bacteriol.
189
4391-4400
2007
41756
Drevland R.M.,Jia Y.,Palmer D.R.J.,Graham D.E.
Methanogen homoaconitase catalyzes both hydrolyase reactions in coenzyme B biosynthesis.
J. Biol. Chem.
283
28888-28896
2008
41757
Jeyakanthan J.,Drevland R.M.,Gayathri D.R.,Velmurugan D.,Shinkai A.,Kuramitsu S.,Yokoyama S.,Graham D.E.
Substrate specificity determinants of the methanogen homoaconitase enzyme: structure and function of the small subunit.
Biochemistry
49
2687-2696
2010
