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Sequence of COLY_YERPE

EC Number:3.4.23.48

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
plasminogen activator Pla
P17811
Yersinia pestis
312
34611
Reaction
Converts human Glu-plasminogen to plasmin by cleaving the Arg560-/-Val peptide bond that is also hydrolysed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins
Other sequences found for EC No. 3.4.23.48

General information:

Sequence
show sequence in fasta format
  0 MKKSSIVATI ITILSGSANA ASSQLIPNIS PDSFTVAAST GMLSGKSHEM LYDAETGRKI
 60 SQLDWKIKNV AILKGDISWD PYSFLTLNAR GWTSLASGSG NMDDYDWMNE NQSEWTDHSS
120 HPATNVNHAN EYDLNVKGWL LQDENYKAGI TAGYQETRFS WTATGGSYSY NNGAYTGNFP
180 KGVRVIGYNQ RFSMPYIGLA GQYRINDFEL NALFKFSDWV RAHDNDEHYM RDLTFREKTS
240 GSRYYGTVIN AGYYVTPNAK VFAEFTYSKY DEGKGGTQTI DKNSGDSVSI GGDAAGISNK
300 NYTVTAGLQY RF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
403839
McDonough K.A.,Falkow S.
A Yersinia pestis-specific DNA fragment encodes temperature-dependent coagulase and fibrinolysin-associated phenotypes.
Mol. Microbiol.
3
767-775
1989
403840
Sodeinde O.A.,Goguen J.D.
Nucleotide sequence of the plasminogen activator gene of Yersinia pestis: relationship to ompT of Escherichia coli and gene E of Salmonella typhimurium.
Infect. Immun.
57
1517-1523
1989
403841
Hu P.,Elliott J.,McCready P.,Skowronski E.,Garnes J.,Kobayashi A.,Brubaker R.R.,Garcia E.
Structural organization of virulence-associated plasmids of Yersinia pestis.
J. Bacteriol.
180
5192-5202
1998
403842
Parkhill J.,Wren B.W.,Thomson N.R.,Titball R.W.,Holden M.T.G.,Prentice M.B.,Sebaihia M.,James K.D.,Churcher C.M.,Mungall K.L.,Baker S.,Basham D.,Bentley S.D.,Brooks K.,Cerdeno-Tarraga A.-M.,Chillingworth T.,Cronin A.,Davies R.M.,Davis P.,Dougan G.,Feltwell T.,Hamlin N.,Holroyd S.,Jagels K.,Karlyshev A.V.,Leather S.,Moule S.,Oyston P.C.F.,Quail M.A.,Rutherford K.M.,Simmonds M.,Skelton J.,Stevens K.,Whitehead S.,Barrell B.G.
Genome sequence of Yersinia pestis, the causative agent of plague.
Nature
413
523-527
2001
403843
Song Y.,Tong Z.,Wang J.,Wang L.,Guo Z.,Han Y.,Zhang J.,Pei D.,Zhou D.,Qin H.,Pang X.,Han Y.,Zhai J.,Li M.,Cui B.,Qi Z.,Jin L.,Dai R.,Chen F.,Li S.,Ye C.,Du Z.,Lin W.,Wang J.,Yu J.,Yang H.,Wang J.,Huang P.,Yang R.
Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.
DNA Res.
11
179-197
2004