Sequence of CEL_HUMAN

sterol esterase

P19835

753

79322

400361

Nilsson J.,Blaeckberg L.,Carlsson P.,Enerbaeck S.,Hernell O.,Bjursell G.

cDNA cloning of human-milk bile-salt-stimulated lipase and evidence for its identity to pancreatic carboxylic ester hydrolase.

Eur. J. Biochem.

192

543-550

1990

400362

Hui D.Y.,Kissel J.A.

Sequence identity between human pancreatic cholesterol esterase and bile salt-stimulated milk lipase.

FEBS Lett.

276

131-134

1990

400363

Baba T.,Downs D.,Jackson K.W.,Tang J.,Wang C.-S.

Structure of human milk bile salt activated lipase.

Biochemistry

30

500-510

1991

400364

Lidberg U.,Nilsson J.,Stroemberg K.,Stenman G.,Sahlin P.,Enerbaeck S.,Bjursell G.

Genomic organization, sequence analysis, and chromosomal localization of the human carboxyl ester lipase (CEL) gene and a CEL-like (CELL) gene.

Genomics

13

630-640

1992

400365

Roudani S.,Miralles F.,Margotat A.,Escribano M.J.,Lombardo D.

Bile salt-dependent lipase transcripts in human fetal tissues.

Biochim. Biophys. Acta

1264

141-150

1995

400366

Madeyski K.,Lidberg U.,Bjursell G.,Nilsson J.

Structure and organization of the human carboxyl ester lipase locus.

Mamm. Genome

9

334-338

1998

400367

Humphray S.J.,Oliver K.,Hunt A.R.,Plumb R.W.,Loveland J.E.,Howe K.L.,Andrews T.D.,Searle S.,Hunt S.E.,Scott C.E.,Jones M.C.,Ainscough R.,Almeida J.P.,Ambrose K.D.,Ashwell R.I.S.,Babbage A.K.,Babbage S.,Bagguley C.L.,Bailey J.,Banerjee R.,Barker D.J.,Barlow K.F.,Bates K.,Beasley H.,Beasley O.,Bird C.P.,Bray-Allen S.,Brown A.J.,Brown J.Y.,Burford D.,Burrill W.,Burton J.,Carder C.,Carter N.P.,Chapman J.C.,Chen Y.,Clarke G.,Clark S.Y.,Clee C.M.,Clegg S.,Collier R.E.,Corby N.,Crosier M.,Cummings A.T.,Davies J.,Dhami P.,Dunn M.,Dutta I.,Dyer L.W.,Earthrowl M.E.,Faulkner L.,Fleming C.J.,Frankish A.,Frankland J.A.,French L.,Fricker D.G.,Garner P.,Garnett J.,Ghori J.,Gilbert J.G.R.,Glison C.,Grafham D.V.,Gribble S.,Griffiths C.,Griffiths-Jones S.,Grocock R.,Guy J.,Hall R.E.,Hammond S.,Harley J.L.,Harrison E.S.I.,Hart E.A.,Heath P.D.,Henderson C.D.,Hopkins B.L.,Howard P.J.,Howden P.J.,Huckle E.,Johnson C.,Johnson D.,Joy A.A.,Kay M.,Keenan S.,Kershaw J.K.,Kimberley A.M.,King A.,Knights A.,Laird G.K.,Langford C.,Lawlor S.,Leongamornlert D.A.,Leversha M.,Lloyd C.,Lloyd D.M.,Lovell J.,Martin S.,Mashreghi-Mohammadi M.,Matthews L.,McLaren S.,McLay K.E.,McMurray A.,Milne S.,Nickerson T.,Nisbett J.,Nordsiek G.,Pearce A.V.,Peck A.I.,Porter K.M.,Pandian R.,Pelan S.,Phillimore B.,Povey S.,Ramsey Y.,Rand V.,Scharfe M.,Sehra H.K.,Shownkeen R.,Sims S.K.,Skuce C.D.,Smith M.,Steward C.A.,Swarbreck D.,Sycamore N.,Tester J.,Thorpe A.,Tracey A.,Tromans A.,Thomas D.W.,Wall M.,Wallis J.M.,West A.P.,Whitehead S.L.,Willey D.L.,Williams S.A.,Wilming L.,Wray P.W.,Young L.,Ashurst J.L.,Coulson A.,Blocker H.,Durbin R.M.,Sulston J.E.,Hubbard T.,Jackson M.J.,Bentley D.R.,Beck S.,Rogers J.,Dunham I.

DNA sequence and analysis of human chromosome 9.

Nature

429

369-374

2004

400369

Hui D.Y.,Hayakawa K.,Oizumi J.

Lipoamidase activity in normal and mutagenized pancreatic cholesterol esterase (bile salt-stimulated lipase).

Biochem. J.

291

65-69

1993

400370

Christie D.L.,Cleverly D.R.,O'Connor C.J.O.

Human milk bile-salt stimulated lipase. Sequence similarity with rat lysophospholipase and homology with the active site region of cholinesterases.

FEBS Lett.

278

190-194

1991

400371

Wang C.S.,Dashti A.,Jackson K.W.,Yeh J.C.,Cummings R.D.,Tang J.

Isolation and characterization of human milk bile salt-activated lipase C-tail fragment.

Biochemistry

34

10639-10644

1995

400372

Mechref Y.,Chen P.,Novotny M.V.

Structural characterization of the N-linked oligosaccharides in bile salt-stimulated lipase originated from human breast milk.

Glycobiology

9

227-234

1999

400373

Tanaka H.,Mierau I.,Ito F.

Purification and characterization of bovine pancreatic bile salt-activated lipase.

J. Biochem.

125

883-890

1999

400374

Ackerman S.J.,Liu L.,Kwatia M.A.,Savage M.P.,Leonidas D.D.,Swaminathan G.J.,Acharya K.R.

Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion.

J. Biol. Chem.

277

14859-14868

2002

400375

Higuchi S.,Nakamura Y.,Saito S.

Characterization of a VNTR polymorphism in the coding region of the CEL gene.

J. Hum. Genet.

47

213-215

2002

400376

Raeder H.,Johansson S.,Holm P.I.,Haldorsen I.S.,Mas E.,Sbarra V.,Nermoen I.,Eide S.A.,Grevle L.,Bjoerkhaug L.,Sagen J.V.,Aksnes L.,Soevik O.,Lombardo D.,Molven A.,Njoelstad P.R.

Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction.

Nat. Genet.

38

54-62

2006

400377

Torsvik J.,Johansson S.,Johansen A.,Ek J.,Minton J.,Raeder H.,Ellard S.,Hattersley A.,Pedersen O.,Hansen T.,Molven A.,Njoelstad P.R.

Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes.

Hum. Genet.

127

55-64

2010

400378

Johansson B.B.,Torsvik J.,Bjoerkhaug L.,Vesterhus M.,Ragvin A.,Tjora E.,Fjeld K.,Hoem D.,Johansson S.,Raeder H.,Lindquist S.,Hernell O.,Cnop M.,Saraste J.,Flatmark T.,Molven A.,Njoelstad P.R.

Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease.

J. Biol. Chem.

286

34593-34605

2011

400379

Kolar M.J.,Kamat S.S.,Parsons W.H.,Homan E.A.,Maher T.,Peroni O.D.,Syed I.,Fjeld K.,Molven A.,Kahn B.B.,Cravatt B.F.,Saghatelian A.

Branched fatty acid esters of hydroxy fatty acids are preferred substrates of the MODY8 protein carboxyl ester lipase.

Biochemistry

55

4636-4641

2016

400380

Xiao X.,Jones G.,Sevilla W.A.,Stolz D.B.,Magee K.E.,Haughney M.,Mukherjee A.,Wang Y.,Lowe M.E.

A carboxyl ester lipase (CEL) mutant causes chronic pancreatitis by forming intracellular aggregates that activate apoptosis.

J. Biol. Chem.

291

23224-23236

2016

400381

Terzyan S.,Wang C.S.,Downs D.,Hunter B.,Zhang X.C.

Crystal structure of the catalytic domain of human bile salt activated lipase.

Protein Sci.

9

1783-1790

2000