Sequence of PGL1_CAEEL

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ribonuclease T1
Q9TZQ3
Caenorhabditis elegans
730
78454
Reaction
two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MEANKREIVD FGGLRSYFFP NLAHYITKND EELFNNTSQA NKLAAFVLGA SKDAPGDEDI
 60 LEMILPNDAN AAVIAAGMDV CLLLGDKFRP KFDAAAEKLS GLGHAHDLVS VIDDDKKLGM
120 LARKAKLKKT EDAKILQALL KVIAIDDAAE KFVELTELVS QLDLDFDVYV LTKILGLISE
180 ETSDEVDIIR DNVVNAFDSC KPLLKQLMLD GPKSEPADPF ISLLMDPLEE SVGKVVNHIA
240 QLFEEASKNE GDESLVLRSQ LGYQLFFLIV RSLADGKREV SKKILSGIPT SVRAEVFPGL
300 QRSVYKSAVF LGNHIIQVLL GSKKSFEDWD VVGVAKDLES AWKRRAIAEL IKKFQVSILE
360 QCFDKPVPLI PQSPLNNDAV IDNVNKALQF ALWLTEFYGS ENETEALGEL RFLDSTSKNL
420 LVDSFKKFVQ GINSKTHVTR IVESLEKCCL SDTPSGRKSN VQPSTSQQQD SAYTKEEMTT
480 VHNTYSVNTK AQVLNGLSDT NSSGLLVDSK DSLSLQEISC DEVDSSTLLS SSRNIGEGVT
540 VKAVDPVPEK VNDAQQQQTV NEIEMASDAN QDTSSSASPE VAPSFSTDGW DSPTKSVALP
600 PGMQQIDEEE TTVADKDSTP QPQARAETAW GSGDATPMPL PAPTNQYKVS GFGEAKVAKG
660 FGQFAPTSSA YGGGGGRGGY GGGDRGGRGG YGGDRGGRGG YGGGDRGGRG GYGGDRGRGG
720 YGGRGGRGGF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
324710
Kawasaki I.,Shim Y.-H.,Kirchner J.,Kaminker J.,Wood W.B.,Strome S.
pgl-1, a predicted RNA-binding component of germ granules, is essential for fertility in C. elegans.
Cell
94
635-645
1998
324711
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
324712
Amiri A.,Keiper B.D.,Kawasaki I.,Fan Y.,Kohara Y.,Rhoads R.E.,Strome S.
An isoform of eIF4E is a component of germ granules and is required for spermatogenesis in C. elegans.
Development
128
3899-3912
2001
324713
Kawasaki I.,Amiri A.,Fan Y.,Meyer N.,Dunkelbarger S.,Motohashi T.,Karashima T.,Bossinger O.,Strome S.
The PGL family proteins associate with germ granules and function redundantly in Caenorhabditis elegans germline development.
Genetics
167
645-661
2004
324714
Tian E.,Wang F.,Han J.,Zhang H.
epg-1 functions in autophagy-regulated processes and may encode a highly divergent Atg13 homolog in C. elegans.
Autophagy
5
608-615
2009
324715
Zhang Y.,Yan L.,Zhou Z.,Yang P.,Tian E.,Zhang K.,Zhao Y.,Li Z.,Song B.,Han J.,Miao L.,Zhang H.
SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans.
Cell
136
308-321
2009
324716
Hanazawa M.,Yonetani M.,Sugimoto A.
PGL proteins self associate and bind RNPs to mediate germ granule assembly in C. elegans.
J. Cell Biol.
192
929-937
2011
324717
Li S.,Yang P.,Tian E.,Zhang H.
Arginine methylation modulates autophagic degradation of PGL granules in C. elegans.
Mol. Cell
52
421-433
2013
324718
Updike D.L.,Knutson A.K.,Egelhofer T.A.,Campbell A.C.,Strome S.
Germ-granule components prevent somatic development in the C. elegans germline.
Curr. Biol.
24
970-975
2014
324719
Min H.,Shim Y.H.,Kawasaki I.
Loss of PGL-1 and PGL-3, members of a family of constitutive germ-granule components, promotes germline apoptosis in C. elegans.
J. Cell Sci.
129
341-353
2016
324720
Al-Amin M.,Min H.,Shim Y.H.,Kawasaki I.
Somatically expressed germ-granule components, PGL-1 and PGL-3, repress programmed cell death in C. elegans.
Sci. Rep.
6
33884-33884
2016
324721
Zhang G.,Lin L.,Qi D.,Zhang H.
The composition of a protein aggregate modulates the specificity and efficiency of its autophagic degradation.
Autophagy
13
1487-1495
2017
324722
Aoki S.T.,Kershner A.M.,Bingman C.A.,Wickens M.,Kimble J.
PGL germ granule assembly protein is a base-specific, single-stranded RNase.
Proc. Natl. Acad. Sci. U.S.A.
113
1279-1284
2016