Sequence of LOX15_RABIT
EC Number:1.13.11.31
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
arachidonate + O2 = (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
Other sequences found for EC No. 1.13.11.31
General information:
Sequence
0 MGVYRVCVST GASIYAGSKN KVELWLVGQH GEVELGSCLR PTRNKEEEFK VNVSKYLGSL
60 LFVRLRKKHF LKEDAWFCNW ISVQALGAAE DKYWFPCYRW VVGDGVQSLP VGTGCTTVGD
120 PQGLFQKHRE QELEERRKLY QWGSWKEGLI LNVAGSKLTD LPVDERFLED KKIDFEASLA
180 WGLAELALKN SLNILAPWKT LDDFNRIFWC GRSKLARRVR DSWQEDSLFG YQFLNGANPM
240 LLRRSVQLPA RLVFPPGMEE LQAQLEKELK AGTLFEADFA LLDNIKANVI LYCQQYLAAP
300 LVMLKLQPDG KLMPMVIQLH LPKIGSSPPP LFLPTDPPMV WLLAKCWVRS SDFQVHELNS
360 HLLRGHLMAE VFTVATMRCL PSIHPVFKLI VPHLRYTLEI NVRARNGLVS DFGIFDQIMS
420 TGGGGHVQLL QQAGAFLTYR SFCPPDDLAD RGLLGVESSF YAQDALRLWE IISRYVQGIM
480 GLYYKTDEAV RDDLELQSWC REITEIGLQG AQKQGFPTSL QSVAQACHFV TMCIFTCTGQ
540 HSSIHLGQLD WFTWVPNAPC TMRLPPPTTK DATLETVMAT LPNLHQSSLQ MSIVWQLGRD
600 QPIMVPLGQH QEEYFSGPEP RAVLEKFREE LAIMDKEIEV RNEKLDIPYE YLRPSIVENS
660 VAI
Download this sequence
in fasta formatDownload all sequences for 1.13.11.31
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
313881
O'Prey J.,Chester J.,Thiele B.J.,Janetzki S.,Prehn S.,Fleming J.,Harrison P.R.
The promoter structure and complete sequence of the gene encoding the rabbit erythroid cell-specific 15-lipoxygenase.
Gene
84
493-499
1989
313882
Berger M.,Schwarz K.,Thiele H.,Reimann I.,Huth A.,Borngraeber S.,Kuehn H.,Thiele B.-J.
Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits.
J. Mol. Biol.
278
935-948
1998
313883
Fleming J.,Thiele B.J.,Chester J.,O'Prey J.,Janetzki S.,Aitken A.,Anton I.A.,Rapoport S.M.,Harrison P.R.
The complete sequence of the rabbit erythroid cell-specific 15-lipoxygenase mRNA: comparison of the predicted amino acid sequence of the erythrocyte lipoxygenase with other lipoxygenases.
Gene
79
181-188
1989
313884
Thiele B.J.,Fleming J.,Kasturi K.,O'Prey J.,Black E.,Chester J.,Rapoport S.M.,Harrison P.R.
Cloning of a rabbit erythroid-cell-specific lipoxygenase mRNA.
Gene
57
111-119
1987
313885
Thiele B.J.,Fleming J.,Chester J.,O'Prey J.,Prehn S.,Janetzki S.,Rapoport S.M.,Harrison P.R.
Structure of the mRNA and of the gene coding for the rabbit erythroid 15-lipoxygenase.
Biomed. Biochim. Acta
49
0-0
1990
313886
Brinckmann R.,Schnurr K.,Heydeck D.,Rosenbach T.,Kolde G.,Kuehn H.
Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme.
Blood
91
64-74
1998
313887
Nigam S.,Patabhiraman S.,Ciccoli R.,Ishdorj G.,Schwarz K.,Petrucev B.,Kuehn H.,Haeggstroem J.Z.
The rat leukocyte-type 12-lipoxygenase exhibits an intrinsic hepoxilin A3 synthase activity.
J. Biol. Chem.
279
29023-29030
2004
313888
Prusakiewicz J.J.,Turman M.V.,Vila A.,Ball H.L.,Al-Mestarihi A.H.,Di Marzo V.,Marnett L.J.
Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases.
Arch. Biochem. Biophys.
464
260-268
2007
313889
Turman M.V.,Kingsley P.J.,Rouzer C.A.,Cravatt B.F.,Marnett L.J.
Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine.
Biochemistry
47
3917-3925
2008
313890
Gillmor S.A.,Villasenor A.,Fletterick R.,Sigal E.,Browner M.F.
The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity.
Nat. Struct. Biol.
4
1003-1009
1997
