Sequence of HICDH_PYRHO
EC Number:1.1.1.286
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
isocitrate-homoisocitrate dehydrogenase
O59394
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
345
38735
Reaction
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+
Other sequences found for EC No. 1.1.1.286
General information:
Sequence
0 MYKVAVIKGD GIGPEVIDAA IRVVKSVTDK IKFYEFEGGL SVFKKYGVPI REEDLEEIRK
60 MDAILFGATT TPFDVPRYKS LIITLRKELD LYANLRIIPN FKLRKEIIIV RENSEGLYSG
120 EGAYDSNKVV DFRIITRKGA ERIAKFAVKL AKDRSTFLTF VHKANILESD RFFRKIVLDI
180 ARKEDVKVRE EIVDSFTIKL VKDPWNLGII LSENMFGDIL SDLATIHAGS IGIVPSGNYG
240 EDIALFEPIH GSAPDIAGKG IANPIGAILS AAMMLDYLGL DGSIIWKAVG RYVRRGNLTP
300 DMEGRATTLE VTNGIISEIY RLDEYEIDEV WRDEVRLGRI LLEIS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
302238
Kawarabayasi Y.,Sawada M.,Horikawa H.,Haikawa Y.,Hino Y.,Yamamoto S.,Sekine M.,Baba S.,Kosugi H.,Hosoyama A.,Nagai Y.,Sakai M.,Ogura K.,Otsuka R.,Nakazawa H.,Takamiya M.,Ohfuku Y.,Funahashi T.,Tanaka T.,Kudoh Y.,Yamazaki J.,Kushida N.,Oguchi A.,Aoki K.,Yoshizawa T.,Nakamura Y.,Robb F.T.,Horikoshi K.,Masuchi Y.,Shizuya H.,Kikuchi H.
Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.
DNA Res.
5
55-76
1998
302239
Miyazaki K.
Bifunctional isocitrate-homoisocitrate dehydrogenase: a missing link in the evolution of beta-decarboxylating dehydrogenase.
Biochem. Biophys. Res. Commun.
331
341-346
2005
