Sequence of ACON_HUMAN
EC Number:4.2.1.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
citrate = cis-aconitate + H2O
Other sequences found for EC No. 4.2.1.3
General information:
Sequence
0 MAPYSLLVTR LQKALGVRQY HVASVLCQRA KVAMSHFEPN EYIHYDLLEK NINIVRKRLN
60 RPLTLSEKIV YGHLDDPASQ EIERGKSYLR LRPDRVAMQD ATAQMAMLQF ISSGLSKVAV
120 PSTIHCDHLI EAQVGGEKDL RRAKDINQEV YNFLATAGAK YGVGFWKPGS GIIHQIILEN
180 YAYPGVLLIG TDSHTPNGGG LGGICIGVGG ADAVDVMAGI PWELKCPKVI GVKLTGSLSG
240 WSSPKDVILK VAGILTVKGG TGAIVEYHGP GVDSISCTGM ATICNMGAEI GATTSVFPYN
300 HRMKKYLSKT GREDIANLAD EFKDHLVPDP GCHYDQLIEI NLSELKPHIN GPFTPDLAHP
360 VAEVGKVAEK EGWPLDIRVG LIGSCTNSSY EDMGRSAAVA KQALAHGLKC KSQFTITPGS
420 EQIRATIERD GYAQILRDLG GIVLANACGP CIGQWDRKDI KKGEKNTIVT SYNRNFTGRN
480 DANPETHAFV TSPEIVTALA IAGTLKFNPE TDYLTGTDGK KFRLEAPDAD ELPKGEFDPG
540 QDTYQHPPKD SSGQHVDVSP TSQRLQLLEP FDKWDGKDLE DLQILIKVKG KCTTDHISAA
600 GPWLKFRGHL DNISNNLLIG AINIENGKAN SVRNAVTQEF GPVPDTARYY KKHGIRWVVI
660 GDENYGEGSS REHAALEPRH LGGRAIITKS FARIHETNLK KQGLLPLTFA DPADYNKIHP
720 VDKLTIQGLK DFTPGKPLKC IIKHPNGTQE TILLNHTFNE TQIEWFRAGS ALNRMKELQQ
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
261058
Mirel D.B.,Marder K.,Graziano J.,Freyer G.,Zhao Q.,Mayeux R.,Wilhelmsen K.C.
Characterization of the human mitochondrial aconitase gene (ACO2).
Gene
213
205-218
1998
261059
Collins J.E.,Wright C.L.,Edwards C.A.,Davis M.P.,Grinham J.A.,Cole C.G.,Goward M.E.,Aguado B.,Mallya M.,Mokrab Y.,Huckle E.J.,Beare D.M.,Dunham I.
A genome annotation-driven approach to cloning the human ORFeome.
Genome Biol.
5
0-0
2004
261061
Dunham I.,Hunt A.R.,Collins J.E.,Bruskiewich R.,Beare D.M.,Clamp M.,Smink L.J.,Ainscough R.,Almeida J.P.,Babbage A.K.,Bagguley C.,Bailey J.,Barlow K.F.,Bates K.N.,Beasley O.P.,Bird C.P.,Blakey S.E.,Bridgeman A.M.,Buck D.,Burgess J.,Burrill W.D.,Burton J.,Carder C.,Carter N.P.,Chen Y.,Clark G.,Clegg S.M.,Cobley V.E.,Cole C.G.,Collier R.E.,Connor R.,Conroy D.,Corby N.R.,Coville G.J.,Cox A.V.,Davis J.,Dawson E.,Dhami P.D.,Dockree C.,Dodsworth S.J.,Durbin R.M.,Ellington A.G.,Evans K.L.,Fey J.M.,Fleming K.,French L.,Garner A.A.,Gilbert J.G.R.,Goward M.E.,Grafham D.V.,Griffiths M.N.D.,Hall C.,Hall R.E.,Hall-Tamlyn G.,Heathcott R.W.,Ho S.,Holmes S.,Hunt S.E.,Jones M.C.,Kershaw J.,Kimberley A.M.,King A.,Laird G.K.,Langford C.F.,Leversha M.A.,Lloyd C.,Lloyd D.M.,Martyn I.D.,Mashreghi-Mohammadi M.,Matthews L.H.,Mccann O.T.,Mcclay J.,Mclaren S.,McMurray A.A.,Milne S.A.,Mortimore B.J.,Odell C.N.,Pavitt R.,Pearce A.V.,Pearson D.,Phillimore B.J.C.T.,Phillips S.H.,Plumb R.W.,Ramsay H.,Ramsey Y.,Rogers L.,Ross M.T.,Scott C.E.,Sehra H.K.,Skuce C.D.,Smalley S.,Smith M.L.,Soderlund C.,Spragon L.,Steward C.A.,Sulston J.E.,Swann R.M.,Vaudin M.,Wall M.,Wallis J.M.,Whiteley M.N.,Willey D.L.,Williams L.,Williams S.A.,Williamson H.,Wilmer T.E.,Wilming L.,Wright C.L.,Hubbard T.,Bentley D.R.,Beck S.,Rogers J.,Shimizu N.,Minoshima S.,Kawasaki K.,Sasaki T.,Asakawa S.,Kudoh J.,Shintani A.,Shibuya K.,Yoshizaki Y.,Aoki N.,Mitsuyama S.,Roe B.A.,Chen F.,Chu L.,Crabtree J.,Deschamps S.,Do A.,Do T.,Dorman A.,Fang F.,Fu Y.,Hu P.,Hua A.,Kenton S.,Lai H.,Lao H.I.,Lewis J.,Lewis S.,Lin S.-P.,Loh P.,Malaj E.,Nguyen T.,Pan H.,Phan S.,Qi S.,Qian Y.,Ray L.,Ren Q.,Shaull S.,Sloan D.,Song L.,Wang Q.,Wang Y.,Wang Z.,White J.,Willingham D.,Wu H.,Yao Z.,Zhan M.,Zhang G.,Chissoe S.,Murray J.,Miller N.,Minx P.,Fulton R.,Johnson D.,Bemis G.,Bentley D.,Bradshaw H.,Bourne S.,Cordes M.,Du Z.,Fulton L.,Goela D.,Graves T.,Hawkins J.,Hinds K.,Kemp K.,Latreille P.,Layman D.,Ozersky P.,Rohlfing T.,Scheet P.,Walker C.,Wamsley A.,Wohldmann P.,Pepin K.,Nelson J.,Korf I.,Bedell J.A.,Hillier L.W.,Mardis E.,Waterston R.,Wilson R.,Emanuel B.S.,Shaikh T.,Kurahashi H.,Saitta S.,Budarf M.L.,McDermid H.E.,Johnson A.,Wong A.C.C.,Morrow B.E.,Edelmann L.,Kim U.J.,Shizuya H.,Simon M.I.,Dumanski J.P.,Peyrard M.,Kedra D.,Seroussi E.,Fransson I.,Tapia I.,Bruder C.E.,O'Brien K.P.,Wilkinson P.,Bodenteich A.,Hartman K.,Hu X.,Khan A.S.,Lane L.,Tilahun Y.,Wright H.
The DNA sequence of human chromosome 22.
Nature
402
489-495
1999
261062
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
261064
Baldwin G.S.,Seet K.L.,Callaghan J.,Toncich G.,Toh B.H.,Moritz R.L.,Rubira M.R.,Simpson R.
Purification and partial amino acid sequence of human aconitase.
Protein Seq. Data Anal.
4
63-67
1991
261065
Choudhary C.,Kumar C.,Gnad F.,Nielsen M.L.,Rehman M.,Walther T.C.,Olsen J.V.,Mann M.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science
325
834-840
2009
261066
Olsen J.V.,Vermeulen M.,Santamaria A.,Kumar C.,Miller M.L.,Jensen L.J.,Gnad F.,Cox J.,Jensen T.S.,Nigg E.A.,Brunak S.,Mann M.
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
Sci. Signal.
3
0-0
2010
261067
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
261068
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
261069
Metodiev M.D.,Gerber S.,Hubert L.,Delahodde A.,Chretien D.,Gerard X.,Amati-Bonneau P.,Giacomotto M.C.,Boddaert N.,Kaminska A.,Desguerre I.,Amiel J.,Rio M.,Kaplan J.,Munnich A.,Rotig A.,Rozet J.M.,Besmond C.
Mutations in the tricarboxylic acid cycle enzyme, aconitase 2, cause either isolated or syndromic optic neuropathy with encephalopathy and cerebellar atrophy.
J. Med. Genet.
51
834-838
2014
261070
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
261071
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015
261072
Sjoeblom T.,Jones S.,Wood L.D.,Parsons D.W.,Lin J.,Barber T.D.,Mandelker D.,Leary R.J.,Ptak J.,Silliman N.,Szabo S.,Buckhaults P.,Farrell C.,Meeh P.,Markowitz S.D.,Willis J.,Dawson D.,Willson J.K.V.,Gazdar A.F.,Hartigan J.,Wu L.,Liu C.,Parmigiani G.,Park B.H.,Bachman K.E.,Papadopoulos N.,Vogelstein B.,Kinzler K.W.,Velculescu V.E.
The consensus coding sequences of human breast and colorectal cancers.
Science
314
268-274
2006
261073
Spiegel R.,Pines O.,Ta-Shma A.,Burak E.,Shaag A.,Halvardson J.,Edvardson S.,Mahajna M.,Zenvirt S.,Saada A.,Shalev S.,Feuk L.,Elpeleg O.
Infantile cerebellar-retinal degeneration associated with a mutation in mitochondrial aconitase, ACO2.
Am. J. Hum. Genet.
90
518-523
2012
