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Sequence of URIC_RAT

EC Number:1.7.3.3

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
factor-independent urate hydroxylase
P09118
Rattus norvegicus
303
34934
Reaction
urate + O2 + H2O = 5-hydroxyisourate + H2O2
Other sequences found for EC No. 1.7.3.3

General information:

Sequence
show sequence in fasta format
  0 MAHYHDDYGK NDEVEFVRTG YGKDMVKVLH IQRDGKYHSI KEVATSVQLT LRSKKDYLHG
 60 DNSDIIPTDT IKNTVHVLAK FKGIKSIETF AMNICEHFLS SFSHVTRAHV YVEEVPWKRF
120 EKNGVKHVHA FIHTPTGTHF CDVEQVRNGP PIIHSGIKDL KVLKTTQSGF EGFIKDQFTT
180 LPEVKDRCFA TQVYCKWRYQ NRDVDFEATW GAVRDIVLKK FAGPYDRGEY SPSVQKTLYD
240 IQVLTLSQLP EIEDMEISLP NIHYFNIDMS KMGLINKEEV LLPLDNPYGK ITGTVRRKLP
300 SRL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
247962
Motojima K.,Goto S.
Organization of rat uricase chromosomal gene differs greatly from that of the corresponding plant gene.
FEBS Lett.
264
156-158
1990
247963
Motojima K.,Kanaya S.,Goto S.
Cloning and sequence analysis of cDNA for rat liver uricase.
J. Biol. Chem.
263
16677-16681
1988
247964
Alvares K.,Nemali M.R.,Reddy P.G.,Wang X.D.,Rao M.S.,Reddy J.K.
The nucleotide sequence of a full length cDNA clone encoding rat liver urate oxidase.
Biochem. Biophys. Res. Commun.
158
991-995
1989
247965
Ito M.,Suzuki M.,Takagi Y.
Nucleotide sequence of cDNA and predicted amino acid sequence of rat liver uricase.
Eur. J. Biochem.
173
459-463
1988
247966
Wang X.D.,Kawano H.,Alvares K.,Reddy P.G.,Getto H.,Rao M.S.,Reddy J.K.
Rat urate oxidase: cloning and structural analysis of the gene and 5'-flanking region.
Gene
97
223-229
1991
247967
Ito M.,Nakamura M.,Ogawa H.,Kato S.,Takagi Y.
Structural analysis of the gene encoding rat uricase.
Genomics
11
905-913
1991
247968
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
247969
Reddy P.G.,Nemali M.R.,Reddy M.K.,Reddy M.N.,Yuan P.M.,Yuen S.,Laffler T.G.,Shiroza T.,Kuramitsu H.K.,Usuda N.,Chisholm R.L.,Rao M.S.,Reddy J.K.
Isolation and sequence determination of a cDNA clone for rat peroxisomal urate oxidase: liver-specific expression in the rat.
Proc. Natl. Acad. Sci. U.S.A.
85
9081-9085
1988
247970
Ito M.,Kato S.,Nakmura M.,Go M.,Takagi Y.
Identification of an amino acid residue involved in the substrate-binding site of rat liver uricase by site-directed mutagenesis.
Biochem. Biophys. Res. Commun.
187
101-107
1992
247971
Lundby A.,Secher A.,Lage K.,Nordsborg N.B.,Dmytriyev A.,Lundby C.,Olsen J.V.
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
Nat. Commun.
3
876-876
2012