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Sequence of DEGS2_HUMAN

EC Number:1.14.19.17

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
sphingolipid 4-desaturase
Q6QHC5
Homo sapiens
323
37197
Reaction
a dihydroceramide + 2 ferrocytochrome b5 + O2 + 2 H+ = a (4E)-sphing-4-enine ceramide + 2 ferricytochrome b5 + 2 H2O
Other sequences found for EC No. 1.14.19.17

General information:

Sequence
show sequence in fasta format
  0 MGNSASRSDF EWVYTDQPHT QRRKEILAKY PAIKALMRPD PRLKWAVLVL VLVQMLACWL
 60 VRGLAWRWLL FWAYAFGGCV NHSLTLAIHD ISHNAAFGTG RAARNRWLAV FANLPVGVPY
120 AASFKKYHVD HHRYLGGDGL DVDVPTRLEG WFFCTPARKL LWLVLQPFFY SLRPLCVHPK
180 AVTRMEVLNT LVQLAADLAI FALWGLKPVV YLLASSFLGL GLHPISGHFV AEHYMFLKGH
240 ETYSYYGPLN WITFNVGYHV EHHDFPSIPG YNLPLVRKIA PEYYDHLPQH HSWVKVLWDF
300 VFEDSLGPYA RVKRVYRLAK DGL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
24817
Mizutani Y.,Kihara A.,Igarashi Y.
Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation.
FEBS Lett.
563
93-97
2004
24818
Heilig R.,Eckenberg R.,Petit J.-L.,Fonknechten N.,Da Silva C.,Cattolico L.,Levy M.,Barbe V.,De Berardinis V.,Ureta-Vidal A.,Pelletier E.,Vico V.,Anthouard V.,Rowen L.,Madan A.,Qin S.,Sun H.,Du H.,Pepin K.,Artiguenave F.,Robert C.,Cruaud C.,Bruels T.,Jaillon O.,Friedlander L.,Samson G.,Brottier P.,Cure S.,Segurens B.,Aniere F.,Samain S.,Crespeau H.,Abbasi N.,Aiach N.,Boscus D.,Dickhoff R.,Dors M.,Dubois I.,Friedman C.,Gouyvenoux M.,James R.,Madan A.,Mairey-Estrada B.,Mangenot S.,Martins N.,Menard M.,Oztas S.,Ratcliffe A.,Shaffer T.,Trask B.,Vacherie B.,Bellemere C.,Belser C.,Besnard-Gonnet M.,Bartol-Mavel D.,Boutard M.,Briez-Silla S.,Combette S.,Dufosse-Laurent V.,Ferron C.,Lechaplais C.,Louesse C.,Muselet D.,Magdelenat G.,Pateau E.,Petit E.,Sirvain-Trukniewicz P.,Trybou A.,Vega-Czarny N.,Bataille E.,Bluet E.,Bordelais I.,Dubois M.,Dumont C.,Guerin T.,Haffray S.,Hammadi R.,Muanga J.,Pellouin V.,Robert D.,Wunderle E.,Gauguet G.,Roy A.,Sainte-Marthe L.,Verdier J.,Verdier-Discala C.,Hillier L.W.,Fulton L.,McPherson J.,Matsuda F.,Wilson R.,Scarpelli C.,Gyapay G.,Wincker P.,Saurin W.,Quetier F.,Waterston R.,Hood L.,Weissenbach J.
The DNA sequence and analysis of human chromosome 14.
Nature
421
601-607
2003
24820
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004