Sequence of PPAP_HUMAN
EC Number:3.1.3.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
a phosphate monoester + H2O = an alcohol + phosphate
Other sequences found for EC No. 3.1.3.2
General information:
Sequence
0 MRAAPLLLAR AASLSLGFLF LLFFWLDRSV LAKELKFVTL VFRHGDRSPI DTFPTDPIKE
60 SSWPQGFGQL TQLGMEQHYE LGEYIRKRYR KFLNESYKHE QVYIRSTDVD RTLMSAMTNL
120 AALFPPEGVS IWNPILLWQP IPVHTVPLSE DQLLYLPFRN CPRFQELESE TLKSEEFQKR
180 LHPYKDFIAT LGKLSGLHGQ DLFGIWSKVY DPLYCESVHN FTLPSWATED TMTKLRELSE
240 LSLLSLYGIH KQKEKSRLQG GVLVNEILNH MKRATQIPSY KKLIMYSAHD TTVSGLQMAL
300 DVYNGLLPPY ASCHLTELYF EKGEYFVEMY YRNETQHEPY PLMLPGCSPS CPLERFAELV
360 GPVIPQDWST ECMTTNSHQG TEDSTD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
208125
Sharief F.S.,Li S.S.-L.
Structure of human prostatic acid phosphatase gene.
Biochem. Biophys. Res. Commun.
184
1468-1476
1992
208126
van Etten R.L.,Davidson R.,Stevis P.E.,Macarthur H.,Moore D.L.
Covalent structure, disulfide bonding, and identification of reactive surface and active site residues of human prostatic acid phosphatase.
J. Biol. Chem.
266
2313-2319
1991
208127
Sharief F.S.,Lee H.,Leuderman M.M.,Lundwall A.,Deaven L.L.,Lee C.-L.,Li S.S.-L.
Human prostatic acid phosphatase: cDNA cloning, gene mapping and protein sequence homology with lysosomal acid phosphatase.
Biochem. Biophys. Res. Commun.
160
79-86
1989
208128
Vihko P.,Virkkunen P.,Henttu P.,Roiko K.,Solin T.,Huhtala M.L.
Molecular cloning and sequence analysis of cDNA encoding human prostatic acid phosphatase.
FEBS Lett.
236
275-281
1988
208129
Tailor P.G.,Govindan M.V.,Patel P.C.
Nucleotide sequence of human prostatic acid phosphatase determined from a full-length cDNA clone.
Nucleic Acids Res.
18
4928-4928
1990
208130
Sharief F.S.,Li S.S.-L.
Nucleotide sequence of human prostatic acid phosphatase ACPP gene, including seven Alu repeats.
Biochem. Mol. Biol. Int.
33
561-565
1994
208132
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
208133
Muzny D.M.,Scherer S.E.,Kaul R.,Wang J.,Yu J.,Sudbrak R.,Buhay C.J.,Chen R.,Cree A.,Ding Y.,Dugan-Rocha S.,Gill R.,Gunaratne P.,Harris R.A.,Hawes A.C.,Hernandez J.,Hodgson A.V.,Hume J.,Jackson A.,Khan Z.M.,Kovar-Smith C.,Lewis L.R.,Lozado R.J.,Metzker M.L.,Milosavljevic A.,Miner G.R.,Morgan M.B.,Nazareth L.V.,Scott G.,Sodergren E.,Song X.-Z.,Steffen D.,Wei S.,Wheeler D.A.,Wright M.W.,Worley K.C.,Yuan Y.,Zhang Z.,Adams C.Q.,Ansari-Lari M.A.,Ayele M.,Brown M.J.,Chen G.,Chen Z.,Clendenning J.,Clerc-Blankenburg K.P.,Chen R.,Chen Z.,Davis C.,Delgado O.,Dinh H.H.,Dong W.,Draper H.,Ernst S.,Fu G.,Gonzalez-Garay M.L.,Garcia D.K.,Gillett W.,Gu J.,Hao B.,Haugen E.,Havlak P.,He X.,Hennig S.,Hu S.,Huang W.,Jackson L.R.,Jacob L.S.,Kelly S.H.,Kube M.,Levy R.,Li Z.,Liu B.,Liu J.,Liu W.,Lu J.,Maheshwari M.,Nguyen B.-V.,Okwuonu G.O.,Palmeiri A.,Pasternak S.,Perez L.M.,Phelps K.A.,Plopper F.J.,Qiang B.,Raymond C.,Rodriguez R.,Saenphimmachak C.,Santibanez J.,Shen H.,Shen Y.,Subramanian S.,Tabor P.E.,Verduzco D.,Waldron L.,Wang J.,Wang J.,Wang Q.,Williams G.A.,Wong G.K.-S.,Yao Z.,Zhang J.,Zhang X.,Zhao G.,Zhou J.,Zhou Y.,Nelson D.,Lehrach H.,Reinhardt R.,Naylor S.L.,Yang H.,Olson M.,Weinstock G.,Gibbs R.A.
The DNA sequence, annotation and analysis of human chromosome 3.
Nature
440
1194-1198
2006
208135
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
208136
Risley J.M.,Van Etten R.L.
Structures of the carbohydrate moieties of human prostatic acid phosphatase elucidated by H1 nuclear magnetic resonance spectroscopy.
Arch. Biochem. Biophys.
258
404-412
1987
208137
Zhang Z.,Ostanin K.,Van Etten R.L.
Covalent modification and site-directed mutagenesis of an active site tryptophan of human prostatic acid phosphatase.
Acta Biochim. Pol.
44
659-672
1997
208138
Hiroyama M.,Takenawa T.
Isolation of a cDNA encoding human lysophosphatidic acid phosphatase that is involved in the regulation of mitochondrial lipid biosynthesis.
J. Biol. Chem.
274
29172-29180
1999
208139
Tanaka M.,Kishi Y.,Takanezawa Y.,Kakehi Y.,Aoki J.,Arai H.
Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.
FEBS Lett.
571
197-204
2004
208140
Quintero I.B.,Araujo C.L.,Pulkka A.E.,Wirkkala R.S.,Herrala A.M.,Eskelinen E.-L.,Jokitalo E.,Hellstroem P.A.,Tuominen H.J.,Hirvikoski P.P.,Vihko P.T.
Prostatic acid phosphatase is not a prostate specific target.
Cancer Res.
67
6549-6554
2007
208141
Munch J.,Rucker E.,Standker L.,Adermann K.,Goffinet C.,Schindler M.,Wildum S.,Chinnadurai R.,Rajan D.,Specht A.,Gimenez-Gallego G.,Sanchez P.C.,Fowler D.M.,Koulov A.,Kelly J.W.,Mothes W.,Grivel J.C.,Margolis L.,Keppler O.T.,Forssmann W.G.,Kirchhoff F.
Semen-derived amyloid fibrils drastically enhance HIV infection.
Cell
131
1059-1071
2007
208142
Schroeder B.,Wrocklage C.,Pan C.,Jaeger R.,Koesters B.,Schaefer H.,Elsaesser H.-P.,Mann M.,Hasilik A.
Integral and associated lysosomal membrane proteins.
Traffic
8
1676-1686
2007
208143
Hong S.,Klein E.A.,Das Gupta J.,Hanke K.,Weight C.J.,Nguyen C.,Gaughan C.,Kim K.A.,Bannert N.,Kirchhoff F.,Munch J.,Silverman R.H.
Fibrils of prostatic acid phosphatase fragments boost infections with XMRV (xenotropic murine leukemia virus-related virus), a human retrovirus associated with prostate cancer.
J. Virol.
83
6995-7003
2009
208144
Hauber I.,Hohenberg H.,Holstermann B.,Hunstein W.,Hauber J.
The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection.
Proc. Natl. Acad. Sci. U.S.A.
106
9033-9038
2009
208145
Roan N.R.,Sowinski S.,Munch J.,Kirchhoff F.,Greene W.C.
Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).
J. Biol. Chem.
285
1861-1869
2010
208146
Chuang T.D.,Chen S.J.,Lin F.F.,Veeramani S.,Kumar S.,Batra S.K.,Tu Y.,Lin M.F.
Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth.
J. Biol. Chem.
285
23598-23606
2010
208147
Graddis T.J.,McMahan C.J.,Tamman J.,Page K.J.,Trager J.B.
Prostatic acid phosphatase expression in human tissues.
Int. J. Clin. Exp. Pathol.
4
295-306
2011
208148
Lacount M.W.,Handy G.,Lebioda L.
Structural origins of L(+)-tartrate inhibition of human prostatic acid phosphatase.
J. Biol. Chem.
273
30406-30409
1998
208149
Jakob C.G.,Lewinski K.,Kuciel R.,Ostrowski W.,Lebioda L.
Crystal structure of human prostatic acid phosphatase.
Prostate
42
211-218
2000
208150
Ortlund E.,LaCount M.W.,Lebioda L.
Crystal structures of human prostatic acid phosphatase in complex with a phosphate ion and alpha-benzylaminobenzylphosphonic acid update the mechanistic picture and offer new insights into inhibitor design.
Biochemistry
42
383-389
2003
208151
Nanga R.P.,Brender J.R.,Vivekanandan S.,Popovych N.,Ramamoorthy A.
NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286).
J. Am. Chem. Soc.
131
17972-17979
2009
