Sequence of CD38_HUMAN
EC Number:3.2.2.5
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
NAD+ + H2O = ADP-D-ribose + nicotinamide + H+
Other sequences found for EC No. 3.2.2.5
General information:
Sequence
0 MANCEFSPVS GDKPCCRLSR RAQLCLGVSI LVLILVVVLA VVVPRWRQQW SGPGTTKRFP
60 ETVLARCVKY TEIHPEMRHV DCQSVWDAFK GAFISKHPCN ITEEDYQPLM KLGTQTVPCN
120 KILLWSRIKD LAHQFTQVQR DMFTLEDTLL GYLADDLTWC GEFNTSKINY QSCPDWRKDC
180 SNNPVSVFWK TVSRRFAEAA CDVVHVMLNG SRSKIFDKNS TFGSVEVHNL QPEKVQTLEA
240 WVIHGGREDS RDLCQDPTIK ELESIISKRN IQFSCKNIYR PDKFLQCVKN PEDSSCTSEI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
652550
Jackson D.G.,Bell J.I.
Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation.
J. Immunol.
144
2811-2815
1990
652551
Nata K.,Takamura T.,Karasawa T.,Kumagai T.,Hashioka W.,Tohgo A.,Yonekura H.,Takasawa S.,Nakamura S.,Okamoto H.
Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing.
Gene
186
285-292
1997
652552
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
652553
States D.J.,Walseth T.F.,Lee H.C.
Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD38.
Trends Biochem. Sci.
17
495-495
1992
652554
Takasawa S.,Tohgo A.,Noguchi N.,Koguma T.,Nata K.,Sugimoto T.,Yonekura H.,Okamoto H.
Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP.
J. Biol. Chem.
268
26052-26054
1993
652555
Tohgo A.,Takasawa S.,Noguchi N.,Koguma T.,Nata K.,Sugimoto T.,Furuya Y.,Yonekura H.,Okamoto H.
Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38.
J. Biol. Chem.
269
28555-28557
1994
652556
Hillman R.T.,Green R.E.,Brenner S.E.
An unappreciated role for RNA surveillance.
Genome Biol.
5
0-0
2004
652557
Moreschi I.,Bruzzone S.,Melone L.,De Flora A.,Zocchi E.
NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases.
Biochem. Biophys. Res. Commun.
345
573-580
2006
652558
Chen R.,Jiang X.,Sun D.,Han G.,Wang F.,Ye M.,Wang L.,Zou H.
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
J. Proteome Res.
8
651-661
2009
652559
Wollscheid B.,Bausch-Fluck D.,Henderson C.,O'Brien R.,Bibel M.,Schiess R.,Aebersold R.,Watts J.D.
Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
Nat. Biotechnol.
27
378-386
2009
652560
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
652561
Vaca Jacome A.S.,Rabilloud T.,Schaeffer-Reiss C.,Rompais M.,Ayoub D.,Lane L.,Bairoch A.,Van Dorsselaer A.,Carapito C.
N-terminome analysis of the human mitochondrial proteome.
Proteomics
15
2519-2524
2015
652562
Liu Q.,Kriksunov I.A.,Graeff R.,Munshi C.,Lee H.C.,Hao Q.
Crystal structure of human CD38 extracellular domain.
Structure
13
1331-1339
2005
652563
Yagui K.,Shimada F.,Mimura M.,Hashimoto N.,Suzuki Y.,Tokuyama Y.,Nata K.,Tohgo A.,Ikehata F.,Takasawa S.,Okamoto H.,Makino H.,Saito Y.,Kanatsuka A.
A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro.
Diabetologia
41
1024-1028
1998
