Sequence of ST2B1_HUMAN

steroid sulfotransferase

O00204

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41308

614511

Her C.,Wood T.C.,Eichler E.E.,Mohrenweiser H.W.,Ramagli L.S.,Siciliano M.J.,Weinshilboum R.M.

Human hydroxysteroid sulfotransferase SULT2B1: two enzymes encoded by a single chromosome 19 gene.

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614512

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The DNA sequence and biology of human chromosome 19.

Nature

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529-535

2004

614513

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

614514

Fuda H.,Lee Y.C.,Shimizu C.,Javitt N.B.,Strott C.A.

Mutational analysis of human hydroxysteroid sulfotransferase SULT2B1 isoforms reveals that exon 1B of the SULT2B1 gene produces cholesterol sulfotransferase, whereas exon 1A yields pregnenolone sulfotransferase.

J. Biol. Chem.

277

36161-36166

2002

614515

He D.,Falany C.N.

Characterization of proline-serine-rich carboxyl terminus in human sulfotransferase 2B1b: immunogenicity, subcellular localization, kinetic properties, and phosphorylation.

Drug Metab. Dispos.

34

1749-1755

2006

614516

Cook I.T.,Duniec-Dmuchowski Z.,Kocarek T.A.,Runge-Morris M.,Falany C.N.

24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor activation.

Drug Metab. Dispos.

37

2069-2078

2009

614517

Salman E.D.,He D.,Runge-Morris M.,Kocarek T.A.,Falany C.N.

Site-directed mutagenesis of human cytosolic sulfotransferase (SULT) 2B1b to phospho-mimetic Ser348Asp results in an isoform with increased catalytic activity.

J. Steroid Biochem. Mol. Biol.

127

315-323

2011

614518

Lee K.A.,Fuda H.,Lee Y.C.,Negishi M.,Strott C.A.,Pedersen L.C.

Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.

J. Biol. Chem.

278

44593-44599

2003

614519

Heinz L.,Kim G.J.,Marrakchi S.,Christiansen J.,Turki H.,Rauschendorf M.A.,Lathrop M.,Hausser I.,Zimmer A.D.,Fischer J.

Mutations in SULT2B1 cause autosomal-recessive congenital ichthyosis in humans.

Am. J. Hum. Genet.

100

926-939

2017