Sequence of BIOD1_ECOLI
EC Number:6.3.3.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin
Other sequences found for EC No. 6.3.3.3
General information:
Sequence
0 MSKRYFVTGT DTEVGKTVAS CALLQAAKAA GYRTAGYKPV ASGSEKTPEG LRNSDALALQ
60 RNSSLQLDYA TVNPYTFAEP TSPHIISAQE GRPIESLVMS AGLRALEQQA DWVLVEGAGG
120 WFTPLSDTFT FADWVTQEQL PVILVVGVKL GCINHAMLTA QVIQHAGLTL AGWVANDVTP
180 PGKRHAEYMT TLTRMIPAPL LGEIPWLAEN PENAATGKYI NLALL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
138250
Otsuka A.J.,Buoncristiani M.R.,Howard P.K.,Flamm J.,Johnson O.,Yamamoto R.,Uchida K.,Cook C.,Ruppert J.,Matsuzaki J.
The Escherichia coli biotin biosynthetic enzyme sequences predicted from the nucleotide sequence of the bio operon.
J. Biol. Chem.
263
19577-19585
1988
138251
Alexeev D.,Bury S.M.,Boys C.W.G.,Turner M.A.,Sawyer L.,Ramsey A.J.,Baxter H.C.,Baxter R.L.
Sequence and crystallization of Escherichia coli dethiobiotin synthetase, the penultimate enzyme of biotin biosynthesis.
J. Mol. Biol.
235
774-776
1994
138253
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
138254
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
138255
Eisenberg M.A.,Krell K.
Synthesis of desthiobiotin from 7,8-diaminopelargonic acid in biotin auxotrophs of Escherichia coli K-12.
J. Bacteriol.
98
1227-1231
1969
138256
Krell K.,Eisenberg M.A.
The purification and properties of dethiobiotin synthetase.
J. Biol. Chem.
245
6558-6566
1970
138257
Yang G.,Sandalova T.,Lohman K.,Lindqvist Y.,Rendina A.R.
Active site mutants of Escherichia coli dethiobiotin synthetase: effects of mutations on enzyme catalytic and structural properties.
Biochemistry
36
4751-4760
1997
138258
Salaemae W.,Yap M.Y.,Wegener K.L.,Booker G.W.,Wilce M.C.,Polyak S.W.
Nucleotide triphosphate promiscuity in Mycobacterium tuberculosis dethiobiotin synthetase.
Tuberculosis
95
259-266
2015
138259
Huang W.,Lindqvist Y.,Schneider G.,Gibson K.J.,Flint D.,Lorimer G.
Crystal structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65-A resolution.
Structure
2
407-414
1994
138260
Alexeev D.,Baxter R.L.,Sawyer L.
Mechanistic implications and family relationships from the structure of dethiobiotin synthetase.
Structure
2
1061-1072
1994
138261
Huang W.,Jia J.,Gibson K.J.,Taylor W.S.,Rendina A.R.,Schneider G.,Lindqvist Y.
Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry
34
10985-10995
1995
138262
Kaeck H.,Gibson K.J.,Lindqvist Y.,Schneider G.
Snapshot of a phosphorylated substrate intermediate by kinetic crystallography.
Proc. Natl. Acad. Sci. U.S.A.
95
5495-5500
1998
138263
Kaeck H.,Sandmark J.,Gibson K.J.,Schneider G.,Lindqvist Y.
Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis.
Protein Sci.
7
2560-2566
1998
138264
Sandalova T.,Schneider G.,Kack H.,Lindqvist Y.
Structure of dethiobiotin synthetase at 0.97-A resolution.
Acta Crystallogr. D
55
610-624
1999
