Sequence of TPH1_MOUSE
EC Number:1.14.16.4
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
L-tryptophan + a 5,6,7,8-tetrahydropteridine + O2 = 5-hydroxy-L-tryptophan + a 4a-hydroxy-5,6,7,8-tetrahydropteridine
Other sequences found for EC No. 1.14.16.4
General information:
Sequence
show sequence in normal format
>P17532|tryptophan 5-monooxygenase|EC 1.14.16.4|Mus musculus|Swiss-Prot
MIEDNKENKENKDHSSERGRVTLIFSLENEVGGLIKVLKIFQENHVSLLHIESRKSKQRN
SEFEIFVDCDISREQLNDIFPLLKSHATVLSVDSPDQLTAKEDVMETVPWFPKKISDLDF
CANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTI
FRELNKLYPTHACREYLRNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLS
PRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLAS
LGASEETVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPK
IACKQECLITSFQDVYFVSESFEDAKEKMREFAKTVKRPFGLKYNPYTQSVQVLRDTKSI
TSAMNELRYDLDVISDALARVTRWPSV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
110704
Stoll J.,Kozak C.A.,Goldman D.
Characterization and chromosomal mapping of a cDNA encoding tryptophan hydroxylase from a mouse mastocytoma cell line.
Genomics
7
88-96
1990
110705
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
110706
Walther D.J.,Peter J.U.,Winter S.,Hoeltje M.,Paulmann N.,Grohmann M.,Vowinckel J.,Alamo-Bethencourt V.,Wilhelm C.S.,Ahnert-Hilger G.,Bader M.
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release.
Cell
115
851-862
2003
