Sequence of FUT1_HUMAN
EC Number:2.4.1.69
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R = GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R
Other sequences found for EC No. 2.4.1.69
General information:
Sequence
0 MWLRSHRQLC LAFLLVCVLS VIFFLHIHQD SFPHGLGLSI LCPDRRLVTP PVAIFCLPGT
60 AMGPNASSSC PQHPASLSGT WTVYPNGRFG NQMGQYATLL ALAQLNGRRA FILPAMHAAL
120 APVFRITLPV LAPEVDSRTP WRELQLHDWM SEEYADLRDP FLKLSGFPCS WTFFHHLREQ
180 IRREFTLHDH LREEAQSVLG QLRLGRTGDR PRTFVGVHVR RGDYLQVMPQ RWKGVVGDSA
240 YLRQAMDWFR ARHEAPVFVV TSNGMEWCKE NIDTSQGDVT FAGDGQEATP WKDFALLTQC
300 NHTIMTIGTF GFWAAYLAGG DTVYLANFTL PDSEFLKIFK PEAAFLPEWV GINADLSPLW
360 TLAKP
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1060675
Larsen R.D.,Ernst L.K.,Nair R.P.,Lowe J.B.
Molecular cloning, sequence, and expression of a human GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen.
Proc. Natl. Acad. Sci. U.S.A.
87
6674-6678
1990
1060676
Wagner F.F.,Flegel W.A.
Polymorphism of the h allele and the population frequency of sporadic nonfunctional alleles.
Transfusion
37
284-290
1997
1060677
Kaneko M.,Nishihara S.,Shinya N.,Kudo T.,Iwasaki H.,Seno T.,Okubo Y.,Narimatsu H.
Wide variety of point mutations in the H gene of Bombay and para-Bombay individuals which inactivate H enzyme.
Blood
90
839-849
1997
1060679
Grimwood J.,Gordon L.A.,Olsen A.S.,Terry A.,Schmutz J.,Lamerdin J.E.,Hellsten U.,Goodstein D.,Couronne O.,Tran-Gyamfi M.,Aerts A.,Altherr M.,Ashworth L.,Bajorek E.,Black S.,Branscomb E.,Caenepeel S.,Carrano A.V.,Caoile C.,Chan Y.M.,Christensen M.,Cleland C.A.,Copeland A.,Dalin E.,Dehal P.,Denys M.,Detter J.C.,Escobar J.,Flowers D.,Fotopulos D.,Garcia C.,Georgescu A.M.,Glavina T.,Gomez M.,Gonzales E.,Groza M.,Hammon N.,Hawkins T.,Haydu L.,Ho I.,Huang W.,Israni S.,Jett J.,Kadner K.,Kimball H.,Kobayashi A.,Larionov V.,Leem S.-H.,Lopez F.,Lou Y.,Lowry S.,Malfatti S.,Martinez D.,McCready P.M.,Medina C.,Morgan J.,Nelson K.,Nolan M.,Ovcharenko I.,Pitluck S.,Pollard M.,Popkie A.P.,Predki P.,Quan G.,Ramirez L.,Rash S.,Retterer J.,Rodriguez A.,Rogers S.,Salamov A.,Salazar A.,She X.,Smith D.,Slezak T.,Solovyev V.,Thayer N.,Tice H.,Tsai M.,Ustaszewska A.,Vo N.,Wagner M.,Wheeler J.,Wu K.,Xie G.,Yang J.,Dubchak I.,Furey T.S.,DeJong P.,Dickson M.,Gordon D.,Eichler E.E.,Pennacchio L.A.,Richardson P.,Stubbs L.,Rokhsar D.S.,Myers R.M.,Rubin E.M.,Lucas S.M.
The DNA sequence and biology of human chromosome 19.
Nature
428
529-535
2004
1060680
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1060681
Moehler T.M.,Sauer S.,Witzel M.,Andrulis M.,Garcia-Vallejo J.J.,Grobholz R.,Willhauck-Fleckenstein M.,Greiner A.,Goldschmidt H.,Schwartz-Albiez R.
Involvement of alpha 1-2-fucosyltransferase I (FUT1) and surface-expressed Lewis(y) (CD174) in first endothelial cell-cell contacts during angiogenesis.
J. Cell. Physiol.
215
27-36
2008
1060682
Kelly R.J.,Ernst L.K.,Larsen R.D.,Bryant J.G.,Robinson J.S.,Lowe J.B.
Molecular basis for H blood group deficiency in Bombay (Oh) and para-Bombay individuals.
Proc. Natl. Acad. Sci. U.S.A.
91
5843-5847
1994
1060683
Koda Y.,Soejima M.,Johnson P.H.,Smart E.,Kimura H.
Missense mutation of FUT1 and deletion of FUT2 are responsible for Indian Bombay phenotype of ABO blood group system.
Biochem. Biophys. Res. Commun.
238
21-25
1997
