Sequence of CBPC1_XENLA
EC Number:3.4.17.24
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
This is a subfamily of enzymes that cleave C-terminal and/or side chain amino acids from tubulins. The dual-specificity enzymes can cleave both alpha- and gamma-linked L-glutamate from tubulins, removing the posttranslationally added polyglutamyl side chains from the C-terminal regions. In addition, the enzyme removes two glutamate residues from the C-terminus of beta-tubulin and detyrosinated alpha-tubulin (from which the C-terminal L-tyrosine has been removed by EC 3.4.17.17, tubulinyl-Tyr carboxypeptidase). The latter is cleaved to delta2-tubulin and further to delta3-tubulin.
Other sequences found for EC No. 3.4.17.24
General information:
Sequence
0 MSKVKATAEK CQLNISRIQS LLSQLEKVNA ESLLFDTDNT RYVTAKIFHL AQTQEKTRKE
60 MTAKGSTGIE VILCTLENTR DLQTILNILN ILNELASTAG GRRINALISK GGARILLQLL
120 LSASKESPSN EELMIVLHSL LAKLGPKDKK FGVKARVSGA LNISLNLVKQ NLQNPRLILP
180 CLQVLRVCCM NSVNSAYLGK NGAVEILFKI IGPFTRRNTG LIKVSLDTLA ALLKSRTNAR
240 KAVDRAYVQT LISTYMDWHR HDTRHRHMLI RKGILQCLKS ITNIKIGRKA FIDANGMKTL
300 YNTSQECQAV RTLDPLVNTS SLIMRKCFPK NRLPLPTIKS AFQFQLPFMP TSGPVALLYS
360 MPPEVDDVVD ESDDNEDTDA ETEAEAENED SDQICKNDDI ETDITKLIPG QELGRTLEDL
420 KMYERFFPEL TEDFQEFDLV SNEPKPGAKL GPIIVPTAGE EQPEVPNNFM KNLARRSCNI
480 SLEDESNQRP TFLDMSKNVT NKGNSLDQKV HVDKDGSCYY YSNDIVRDLE KLSLHKASGN
540 HPCRNGCVSA KDKPNFLPHP CNKSTSSSIS CSNSLFEKHS MHLGPLCCSG IAPDDDESSP
600 LDEQVMREMT DFDSILPLHD PDLYIEIVKN TKSVPEYTEV AYPDYFGHVP PFFKERLLER
660 PYGVQRSKIF QDIERMIHPN DIIDRVIYDL DNPSCSAHDE IDILKFNSKF ESGNLRKVIQ
720 IRKNEYDLIL NSDINSNHYH QWFYFEVSGM RTGVAYRFNI INCEKSNSQF NYGMQPLMYS
780 VQEALASRPW WYRVGTDICY YKNHFSRSSL ATGGQKGKSY YTITFTVTFP HKDDVCYFAY
840 HYPYTYSTLK MHLQKLESLH SPQQIYFRQE VLCETLGGNG CPVITITAMP ESNYYEHVYQ
900 FRNRPYIFLT SRVHPGETNA SWVMKGTLEF LMGSSATAQS LRESYIFKIV PMLNPDGVIN
960 GNHRCSLSGE DLNRQWQNPN SDLHPTIYHT KGLLQYLSAI KRVPLVYCDY HGHSRKKNVF
1020 MYGCSIKETV WHTNANAASC DMVEESGYKT LPKVLNQIAP AFSMSSCSFV VEKSKESTAR
1080 VVVWKEIGVQ RSYTMESTLC GCDQGKYKDL QIGTKELEEM GAKFCVGLLR LKRLTSPMEL
1140 TLPPSLIDIE NELIESSCKV ASPTTYVLED DEPRFIEEVD YSAESNDDVD PDLPENIGDF
1200 ETSTLEEESF SDSEITRTHM SGQST
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