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Sequence of 8ODP_RAT

EC Number:3.6.1.56

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2-hydroxy-dATP diphosphatase
P53369
Rattus norvegicus
156
18018
Reaction
2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + diphosphate
Other sequences found for EC No. 3.6.1.56

General information:

Sequence
show sequence in fasta format
  0 MSTSRLYTLV LVLQPQRVLL GMKKRGFGAG RWNGFGGKVQ EGETIEDGAK RELLEESGLR
 60 VDTLHKVGHI SFEFVGSPEL MDVHIFSTDH VHGTPTESEE MRPQWFQLDQ IPFADMWPDD
120 SYWFPLLLQK KKFCGHFKFH GQDTILSYSL REVDEF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
893192
Cai J.P.,Kakuma T.,Tsuzuki T.,Sekiguchi M.
cDNA and genomic sequences for rat 8-oxo-dGTPase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides.
Carcinogenesis
16
2343-2350
1995
893193
Kasprzak K.S.,Nakabeppu Y.,Kakuma T.,Sakai Y.,Tsuruya K.,Sekiguchi M.,Ward J.M.,Diwan B.A.,Nagashima K.,Kasprzak B.H.
Intracellular distribution of the antimutagenic enzyme MTH1 in the liver, kidney and testis of F344 rats and its modulation by cadmium.
Exp. Toxicol. Pathol.
53
325-335
2001
893194
Jemth A.S.,Gustafsson R.,Braeutigam L.,Henriksson L.,Vallin K.S.A.,Sarno A.,Almloef I.,Homan E.,Rasti A.,Warpman Berglund U.,Stenmark P.,Helleday T.
MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP.
Nucleic Acids Res.
46
10888-10904
2018
893195
Scaletti E.R.,Vallin K.S.,Braeutigam L.,Sarno A.,Warpman Berglund U.,Helleday T.,Stenmark P.,Jemth A.S.
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.
J. Biol. Chem.
295
4761-4772
2020