Sequence of KPCT_MOUSE
EC Number:2.7.11.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.13
General information:
Sequence
0 MSPFLRIGLS NFDCGTCQAC QGEAVNPYCA VLVKEYVESE NGQMYIQKKP TMYPPWDSTF
60 DAHINKGRVM QIIVKGKNVD LISETTVELY SLAERCRKNN GRTEIWLELK PQGRMLMNAR
120 YFLEMSDTKD MSEFENEGFF ALHQRRGAIK QAKVHHVKCH EFTATFFPQP TFCSVCHEFV
180 WGLNKQGYQC RQCNAAIHKK CIDKVIAKCT GSAINSRETM FHKERFKIDM PHRFKVYNYK
240 SPTFCEHCGT LLWGLARQGL KCDACGMNVH HRCQTKVANL CGINQKLMAE ALAMIESTQQ
300 ARSLRDSEHI FREGPVEIGL PCSTKNETRP PCVPTPGKRE PQGISWDSPL DGSNKSAGPP
360 EPEVSMRRTS LQLKLKIDDF ILHKMLGKGS FGKVFLAEFK RTNQFFAIKA LKKDVVLMDD
420 DVECTMVEKR VLSLAWEHPF LTHMFCTFQT KENLFFVMEY LNGGDLMYHI QSCHKFDLSR
480 ATFYAAEVIL GLQFLHSKGI VYRDLKLDNI LLDRDGHIKI ADFGMCKENM LGDAKTNTFC
540 GTPDYIAPEI LLGQKYNHSV DWWSFGVLVY EMLIGQSPFH GQDEEELFHS IRMDNPFYPR
600 WLEREAKDLL VKLFVREPEK RLGVRGDIRQ HPLFREINWE ELERKEIDPP FRPKVKSPYD
660 CSNFDKEFLS EKPRLSFADR ALINSMDQNM FSNFSFINPG METLICS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
817404
Osada S.,Mizuno K.,Saido T.C.,Suzuki K.,Kuroki T.,Ohno S.
A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle.
Mol. Cell. Biol.
12
3930-3938
1992
817405
Sun Z.,Arendt C.W.,Ellmeier W.,Schaeffer E.M.,Sunshine M.J.,Gandhi L.,Annes J.,Petrzilka D.,Kupfer A.,Schwartzberg P.L.,Littman D.R.
PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes.
Nature
404
402-407
2000
817406
Pfeifhofer C.,Kofler K.,Gruber T.,Tabrizi N.G.,Lutz C.,Maly K.,Leitges M.,Baier G.
Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells.
J. Exp. Med.
197
1525-1535
2003
817407
Marsland B.J.,Soos T.J.,Spaeth G.,Littman D.R.,Kopf M.
Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses.
J. Exp. Med.
200
181-189
2004
817408
Tan S.L.,Zhao J.,Bi C.,Chen X.C.,Hepburn D.L.,Wang J.,Sedgwick J.D.,Chintalacharuvu S.R.,Na S.
Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice.
J. Immunol.
176
2872-2879
2006
817409
Wang C.,Liu M.,Riojas R.A.,Xin X.,Gao Z.,Zeng R.,Wu J.,Dong L.Q.,Liu F.
Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance.
J. Biol. Chem.
284
2038-2044
2009
817410
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
