Sequence of DDDP_ROSNI
EC Number:4.4.1.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
dimethylpropiothetin dethiomethylase
A3SK19
Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)
446
49971
Reaction
S,S-dimethyl-beta-propiothetin = dimethyl sulfide + acrylate
General information:
Sequence
0 MNQHYSETRK IDPSRGATLG DNTPNDNNRI EIGPTQLAFG EWATAGLALP DLQRMREFRW
60 NRLTQAVVDR DYGGVLMFDP LNIRYATDST NMQLWNAHNP FRALLVCADG YMVIWDYKNS
120 PFLSTFNPLV REQRFGADLF YFDRGDKVDV AADAFSNEVR TLIAEHGGGN MRLAVDKIML
180 HGLRALEAQG FEIMEGEELT EKTRAIKGPD EILAMRCAVH ACETSVAAME HFAREAVPQG
240 NTSEDDVWAV LHAENIKRGG EWIETRLLAS GPRTNPWFQE CGPRIIQNNE IISFDTDLIG
300 SYGICVDISR SWWVGDAAPP ADMVYAMQHA HEHIMTNMEM LKPGVTIPEL SERSHRLDEQ
360 FQAQKYGCLM HGVGLCDEWP LVAYPDQAVP GSYDYPLEPG MVLCVEAAVG AVGGNFTIKL
420 EDQVLITETG YENLTSYPFD PALMGR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
47637
Todd J.D.,Curson A.R.,Dupont C.L.,Nicholson P.,Johnston A.W.
The dddP gene, encoding a novel enzyme that converts dimethylsulfoniopropionate into dimethyl sulfide, is widespread in ocean metagenomes and marine bacteria and also occurs in some Ascomycete fungi.
Environ. Microbiol.
11
1376-1385
2009
47638
Kirkwood M.,Le Brun N.E.,Todd J.D.,Johnston A.W.
The dddP gene of Roseovarius nubinhibens encodes a novel lyase that cleaves dimethylsulfoniopropionate into acrylate plus dimethyl sulfide.
Microbiology
156
1900-1906
2010
47639
Alcolombri U.,Laurino P.,Lara-Astiaso P.,Vardi A.,Tawfik D.S.
DddD is a CoA-transferase/lyase producing dimethyl sulfide in the marine environment.
Biochemistry
53
5473-5475
2014
