Sequence of DDDP_ROSNI
EC Number:4.4.1.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
dimethylpropiothetin dethiomethylase
A3SK19
Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)
446
49971
Reaction
S,S-dimethyl-beta-propiothetin = dimethyl sulfide + acrylate
General information:
Sequence
show sequence in normal format
>A3SK19|dimethylpropiothetin dethiomethylase|EC 4.4.1.3|Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)|Swiss-Prot
MNQHYSETRKIDPSRGATLGDNTPNDNNRIEIGPTQLAFGEWATAGLALPDLQRMREFRW
NRLTQAVVDRDYGGVLMFDPLNIRYATDSTNMQLWNAHNPFRALLVCADGYMVIWDYKNS
PFLSTFNPLVREQRFGADLFYFDRGDKVDVAADAFSNEVRTLIAEHGGGNMRLAVDKIML
HGLRALEAQGFEIMEGEELTEKTRAIKGPDEILAMRCAVHACETSVAAMEHFAREAVPQG
NTSEDDVWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRIIQNNEIISFDTDLIG
SYGICVDISRSWWVGDAAPPADMVYAMQHAHEHIMTNMEMLKPGVTIPELSERSHRLDEQ
FQAQKYGCLMHGVGLCDEWPLVAYPDQAVPGSYDYPLEPGMVLCVEAAVGAVGGNFTIKL
EDQVLITETGYENLTSYPFDPALMGR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
47637
Todd J.D.,Curson A.R.,Dupont C.L.,Nicholson P.,Johnston A.W.
The dddP gene, encoding a novel enzyme that converts dimethylsulfoniopropionate into dimethyl sulfide, is widespread in ocean metagenomes and marine bacteria and also occurs in some Ascomycete fungi.
Environ. Microbiol.
11
1376-1385
2009
47638
Kirkwood M.,Le Brun N.E.,Todd J.D.,Johnston A.W.
The dddP gene of Roseovarius nubinhibens encodes a novel lyase that cleaves dimethylsulfoniopropionate into acrylate plus dimethyl sulfide.
Microbiology
156
1900-1906
2010
47639
Alcolombri U.,Laurino P.,Lara-Astiaso P.,Vardi A.,Tawfik D.S.
DddD is a CoA-transferase/lyase producing dimethyl sulfide in the marine environment.
Biochemistry
53
5473-5475
2014
