Sequence of PDE2A_RAT
EC Number:3.1.4.17
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate
Other sequences found for EC No. 3.1.4.17
General information:
Sequence
0 MVLVLHHILI AVVQFLRRGQ QVFLKPDEPP PQPCADSLQD ALLSLGAVID IAGLRQAAKD
60 ALSAVLPKVE TVYTYLVDGE SRLVCEDPPH ELPQEGKIRE AVISRKRLSC DGLGPSDLLG
120 KPLARLVAPL APDTQVLVIP LLDKETGTVA AVILVHCGQL SDSEEQSLQV VEKHALVALQ
180 RVQALQQRRP EAVQNTSADP SEDQKDEKGY TAHDRKILQL CGELYDLDAT SLQLKVLRYL
240 QQETQATHCC LLLVSEDNLQ LSCKVIGEKV LGEEVSFPLT MGRLGQVVED KQCIQLKDLT
300 SDDVQQLQNM LGCELRAMLC VPVISRATDQ VVALACAFNK LGGDFFTDED ERAIQHCFHY
360 TGTVLTSTLA FQKEQKLKCE CQALLQVAKN LFTHLDDVSV LLQEIITEAR NLSNAEICSV
420 FLLDQNELVA KVFDGGVVDD ESYEIRIPAD QGIAGHVATT GQILNIPDAY AHPLFYRGVD
480 DSTGFRTRNI LCFPIKNENQ EVIGVAELVN KINGPWFSKF DEDLATAFSI YCGISIAHSL
540 LYKKVNEAQY RSHLANEMMM YHMKVSDDEY TKLLHDGIQP VAAIDSNFAN FTYTPRSLPE
600 DDTSMAILSM LQDMNFINNY KIDCPTLARF CLMVKKGYRD PPYHNWMHAF SVSHFCYLLY
660 KNLELSNYLE DIEIFALFIS CMCHDLDHRG TNNSFQVASK SVLAALYSSE GSVMERHHFA
720 QAIAILNTHG CNIFDHFSRK DYQRMLDLMR DIILATDLAH HLRIFKDLQK MAEVGYDRNN
780 KQHHRLLLCL LMTSCDLSDQ TKGWKTTRKI AELIYKEFFS QGDLEKAMGN RPMEMMDREK
840 AYIPELQISF MEHIAMPIYK LLQDLFPKAA ELYERVASNR EHWTKVSHKF TIRGLPSNNS
900 LDFLDEEYEV PDLDVTRAPV NGCCSLEG
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
710553
Yang Q.,Paskind M.,Bolger G.,Thompson W.J.,Repaske D.R.,Cutler L.S.,Epstein P.M.
A novel cyclic GMP stimulated phosphodiesterase from rat brain.
Biochem. Biophys. Res. Commun.
205
1850-1858
1994
710554
Repaske D.R.,Swinnen J.V.,Jin S.-L.C.,van Wyk J.J.,Conti M.
A polymerase chain reaction strategy to identify and clone cyclic nucleotide phosphodiesterase cDNAs. Molecular cloning of the cDNA encoding the 63-kDa calmodulin-dependent phosphodiesterase.
J. Biol. Chem.
267
18683-18688
1992
710555
Acin-Perez R.,Russwurm M.,Gunnewig K.,Gertz M.,Zoidl G.,Ramos L.,Buck J.,Levin L.R.,Rassow J.,Manfredi G.,Steegborn C.
A phosphodiesterase 2A isoform localized to mitochondria regulates respiration.
J. Biol. Chem.
286
30423-30432
2011
710556
Lundby A.,Secher A.,Lage K.,Nordsborg N.B.,Dmytriyev A.,Lundby C.,Olsen J.V.
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
Nat. Commun.
3
876-876
2012
710557
Monterisi S.,Lobo M.J.,Livie C.,Castle J.C.,Weinberger M.,Baillie G.,Surdo N.C.,Musheshe N.,Stangherlin A.,Gottlieb E.,Maizels R.,Bortolozzi M.,Micaroni M.,Zaccolo M.
PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling.
Elife
6
0-0
2017
