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Sequence of GPT2_YEAST

EC Number:2.3.1.42

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glycerone-phosphate O-acyltransferase
P36148
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
743
83645
Reaction
acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate
Other sequences found for EC No. 2.3.1.42

General information:

Sequence
show sequence in fasta format
  0 MSAPAADHNA AKPIPHVPQA SRRYKNSYNG FVYNIHTWLY DVSVFLFNIL FTIFFREIKV
 60 RGAYNVPEVG VPTILVCAPH ANQFIDPALV MSQTRLLKTS AGKSRSRMPC FVTAESSFKK
120 RFISFFGHAM GGIPVPRIQD NLKPVDENLE IYAPDLKNHP EIIKGRSKNP QTTPVNFTKR
180 FSAKSLLGLP DYLSNAQIKE IPDDETIILS SPFRTSKSKV VELLTNGTNF KYAEKIDNTE
240 TFQSVFDHLH TKGCVGIFPE GGSHDRPSLL PIKAGVAIMA LGAVAADPTM KVAVVPCGLH
300 YFHRNKFRSR AVLEYGEPIV VDGKYGEMYK DSPRETVSKL LKKITNSLFS VTENAPDYDT
360 LMVIQAARRL YQPVKVRLPL PAIVEINRRL LFGYSKFKDD PRIIHLKKLV YDYNRKLDSV
420 GLKDHQVMQL KTTKLEALRC FVTLIVRLIK FSVFAILSLP GSILFTPIFI ICRVYSEKKA
480 KEGLKKSLVK IKGTDLLATW KLIVALILAP ILYVTYSILL IILARKQHYC RIWVPSNNAF
540 IQFVYFYALL VFTTYSSLKT GEIGVDLFKS LRPLFVSIVY PGKKIEEIQT TRKNLSLELT
600 AVCNDLGPLV FPDYDKLATE IFSKRDGYDV SSDAESSISR MSVQSRSRSS SIHSIGSLAS
660 NALSRVNSRG SLTDIPIFSD AKQGQWKSEG ETSEDEDEFD EKNPAIVQTA RSSDLNKENS
720 RNTNISSKIA SLVRQKREHE KKE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
677856
Zheng Z.,Zou J.
The initial step of the glycerolipid pathway: identification of glycerol-3-phosphate / dihydroxyacetone phosphate dual substrate acyltransferases in Saccharomyces cerevisiae.
J. Biol. Chem.
276
41710-41716
2001
677857
Dujon B.,Alexandraki D.,Andre B.,Ansorge W.,Baladron V.,Ballesta J.P.G.,Banrevi A.,Bolle P.-A.,Bolotin-Fukuhara M.,Bossier P.,Bou G.,Boyer J.,Buitrago M.J.,Cheret G.,Colleaux L.,Daignan-Fornier B.,del Rey F.,Dion C.,Domdey H.,Duesterhoeft A.,Duesterhus S.,Entian K.-D.,Erfle H.,Esteban P.F.,Feldmann H.,Fernandes L.,Fobo G.M.,Fritz C.,Fukuhara H.,Gabel C.,Gaillon L.,Garcia-Cantalejo J.M.,Garcia-Ramirez J.J.,Gent M.E.,Ghazvini M.,Goffeau A.,Gonzalez A.,Grothues D.,Guerreiro P.,Hegemann J.H.,Hewitt N.,Hilger F.,Hollenberg C.P.,Horaitis O.,Indge K.J.,Jacquier A.,James C.M.,Jauniaux J.-C.,Jimenez A.,Keuchel H.,Kirchrath L.,Kleine K.,Koetter P.,Legrain P.,Liebl S.,Louis E.J.,Maia e Silva A.,Marck C.,Monnier A.-L.,Moestl D.,Mueller S.,Obermaier B.,Oliver S.G.,Pallier C.,Pascolo S.,Pfeiffer F.,Philippsen P.,Planta R.J.,Pohl F.M.,Pohl T.M.,Poehlmann R.,Portetelle D.,Purnelle B.,Puzos V.,Ramezani Rad M.,Rasmussen S.W.,Remacha M.A.,Revuelta J.L.,Richard G.-F.,Rieger M.,Rodrigues-Pousada C.,Rose M.,Rupp T.,Santos M.A.,Schwager C.,Sensen C.,Skala J.,Soares H.,Sor F.,Stegemann J.,Tettelin H.,Thierry A.,Tzermia M.,Urrestarazu L.A.,van Dyck L.,van Vliet-Reedijk J.C.,Valens M.,Vandenbol M.,Vilela C.,Vissers S.,von Wettstein D.,Voss H.,Wiemann S.,Xu G.,Zimmermann J.,Haasemann M.,Becker I.,Mewes H.-W.
Complete DNA sequence of yeast chromosome XI.
Nature
369
371-378
1994
677858
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
677859
Athenstaedt K.,Daum G.
Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiae.
J. Bacteriol.
179
7611-7616
1997
677860
Athenstaedt K.,Weys S.,Paltauf F.,Daum G.
Redundant systems of phosphatidic acid biosynthesis via acylation of glycerol-3-phosphate or dihydroxyacetone phosphate in the yeast Saccharomyces cerevisiae.
J. Bacteriol.
181
1458-1463
1999
677861
Zaremberg V.,McMaster C.R.
Differential partitioning of lipids metabolized by separate yeast glycerol-3-phosphate acyltransferases reveals that phospholipase D generation of phosphatidic acid mediates sensitivity to choline-containing lysolipids and drugs.
J. Biol. Chem.
277
39035-39044
2002
677862
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
677863
Kim H.,Melen K.,Oesterberg M.,von Heijne G.
A global topology map of the Saccharomyces cerevisiae membrane proteome.
Proc. Natl. Acad. Sci. U.S.A.
103
11142-11147
2006
677864
Li X.,Gerber S.A.,Rudner A.D.,Beausoleil S.A.,Haas W.,Villen J.,Elias J.E.,Gygi S.P.
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
J. Proteome Res.
6
1190-1197
2007
677865
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
677866
Bratschi M.W.,Burrowes D.P.,Kulaga A.,Cheung J.F.,Alvarez A.L.,Kearley J.,Zaremberg V.
Glycerol-3-phosphate acyltransferases gat1p and gat2p are microsomal phosphoproteins with differential contributions to polarized cell growth.
Eukaryot. Cell
8
1184-1196
2009
677867
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
677868
Marr N.,Foglia J.,Terebiznik M.,Athenstaedt K.,Zaremberg V.
Controlling lipid fluxes at glycerol-3-phosphate acyltransferase step in yeast: unique contribution of Gat1p to oleic acid-induced lipid particle formation.
J. Biol. Chem.
287
10251-10264
2012
677869
Debelyy M.O.,Waridel P.,Quadroni M.,Schneiter R.,Conzelmann A.
Chemical crosslinking and mass spectrometry to elucidate the topology of integral membrane proteins.
PLoS ONE
12
0-0
2017
677870
Kiegerl B.,Tavassoli M.,Smart H.,Shabits B.N.,Zaremberg V.,Athenstaedt K.
Phosphorylation of the lipid droplet localized glycerol-3-phosphate acyltransferase Gpt2 prevents a futile triacylglycerol cycle in yeast.
Biochim. Biophys. Acta
1864
158509-158509
2019