Sequence of ACAC_YEAST
EC Number:6.3.4.14
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + [biotin carboxyl-carrier protein]-biotin-N6-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N6-L-lysine
Other sequences found for EC No. 6.3.4.14
General information:
Sequence
0 MSEESLFESS PQKMEYEITN YSERHTELPG HFIGLNTVDK LEESPLRDFV KSHGGHTVIS
60 KILIANNGIA AVKEIRSVRK WAYETFGDDR TVQFVAMATP EDLEANAEYI RMADQYIEVP
120 GGTNNNNYAN VDLIVDIAER ADVDAVWAGW GHASENPLLP EKLSQSKRKV IFIGPPGNAM
180 RSLGDKISST IVAQSAKVPC IPWSGTGVDT VHVDEKTGLV SVDDDIYQKG CCTSPEDGLQ
240 KAKRIGFPVM IKASEGGGGK GIRQVEREED FIALYHQAAN EIPGSPIFIM KLAGRARHLE
300 VQLLADQYGT NISLFGRDCS VQRRHQKIIE EAPVTIAKAE TFHEMEKAAV RLGKLVGYVS
360 AGTVEYLYSH DDGKFYFLEL NPRLQVEHPT TEMVSGVNLP AAQLQIAMGI PMHRISDIRT
420 LYGMNPHSAS EIDFEFKTQD ATKKQRRPIP KGHCTACRIT SEDPNDGFKP SGGTLHELNF
480 RSSSNVWGYF SVGNNGNIHS FSDSQFGHIF AFGENRQASR KHMVVALKEL SIRGDFRTTV
540 EYLIKLLETE DFEDNTITTG WLDDLITHKM TAEKPDPTLA VICGAATKAF LASEEARHKY
600 IESLQKGQVL SKDLLQTMFP VDFIHEGKRY KFTVAKSGND RYTLFINGSK CDIILRQLSD
660 GGLLIAIGGK SHTIYWKEEV AATRLSVDSM TTLLEVENDP TQLRTPSPGK LVKFLVENGE
720 HIIKGQPYAE IEVMKMQMPL VSQENGIVQL LKQPGSTIVA GDIMAIMTLD DPSKVKHALP
780 FEGMLPDFGS PVIEGTKPAY KFKSLVSTLE NILKGYDNQV IMNASLQQLI EVLRNPKLPY
840 SEWKLHISAL HSRLPAKLDE QMEELVARSL RRGAVFPARQ LSKLIDMAVK NPEYNPDKLL
900 GAVVEPLADI AHKYSNGLEA HEHSIFVHFL EEYYEVEKLF NGPNVREENI ILKLRDENPK
960 DLDKVALTVL SHSKVSAKNN LILAILKHYQ PLCKLSSKVS AIFSTPLQHI VELESKATAK
1020 VALQAREILI QGALPSVKER TEQIEHILKS SVVKVAYGSS NPKRSEPDLN ILKDLIDSNY
1080 VVFDVLLQFL THQDPVVTAA AAQVYIRRAY RAYTIGDIRV HEGVTVPIVE WKFQLPSAAF
1140 STFPTVKSKM GMNRAVSVSD LSYVANSQSS PLREGILMAV DHLDDVDEIL SQSLEVIPRH
1200 QSSSNGPAPD RSGSSASLSN VANVCVASTE GFESEEEILV RLREILDLNK QELINASIRR
1260 ITFMFGFKDG SYPKYYTFNG PNYNENETIR HIEPALAFQL ELGRLSNFNI KPIFTDNRNI
1320 HVYEAVSKTS PLDKRFFTRG IIRTGHIRDD ISIQEYLTSE ANRLMSDILD NLEVTDTSNS
1380 DLNHIFINFI AVFDISPEDV EAAFGGFLER FGKRLLRLRV SSAEIRIIIK DPQTGAPVPL
1440 RALINNVSGY VIKTEMYTEV KNAKGEWVFK SLGKPGSMHL RPIATPYPVK EWLQPKRYKA
1500 HLMGTTYVYD FPELFRQASS SQWKNFSADV KLTDDFFISN ELIEDENGEL TEVEREPGAN
1560 AIGMVAFKIT VKTPEYPRGR QFVVVANDIT FKIGSFGPQE DEFFNKVTEY ARKRGIPRIY
1620 LAANSGARIG MAEEIVPLFQ VAWNDAANPD KGFQYLYLTS EGMETLKKFD KENSVLTERT
1680 VINGEERFVI KTIIGSEDGL GVECLRGSGL IAGATSRAYH DIFTITLVTC RSVGIGAYLV
1740 RLGQRAIQVE GQPIILTGAP AINKMLGREV YTSNLQLGGT QIMYNNGVSH LTAVDDLAGV
1800 EKIVEWMSYV PAKRNMPVPI LETKDTWDRP VDFTPTNDET YDVRWMIEGR ETESGFEYGL
1860 FDKGSFFETL SGWAKGVVVG RARLGGIPLG VIGVETRTVE NLIPADPANP NSAETLIQEP
1920 GQVWHPNSAF KTAQAINDFN NGEQLPMMIL ANWRGFSGGQ RDMFNEVLKY GSFIVDALVD
1980 YKQPIIIYIP PTGELRGGSW VVVDPTINAD QMEMYADVNA RAGVLEPQGM VGIKFRREKL
2040 LDTMNRLDDK YRELRSQLSN KSLAPEVHQQ ISKQLADRER ELLPIYGQIS LQFADLHDRS
2100 SRMVAKGVIS KELEWTEARR FFFWRLRRRL NEEYLIKRLS HQVGEASRLE KIARIRSWYP
2160 ASVDHEDDRQ VATWIEENYK TLDDKLKGLK LESFAQDLAK KIRSDHDNAI DGLSEVIKML
2220 STDDKEKLLK TLK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
638634
Al-Feel W.,Chirala S.S.,Wakil S.J.
Cloning of the yeast FAS3 gene and primary structure of yeast acetyl-CoA carboxylase.
Proc. Natl. Acad. Sci. U.S.A.
89
4534-4538
1992
638635
Philippsen P.,Kleine K.,Poehlmann R.,Duesterhoeft A.,Hamberg K.,Hegemann J.H.,Obermaier B.,Urrestarazu L.A.,Aert R.,Albermann K.,Altmann R.,Andre B.,Baladron V.,Ballesta J.P.G.,Becam A.-M.,Beinhauer J.D.,Boskovic J.,Buitrago M.J.,Bussereau F.,Coster F.,Crouzet M.,D'Angelo M.,Dal Pero F.,De Antoni A.,del Rey F.,Doignon F.,Domdey H.,Dubois E.,Fiedler T.A.,Fleig U.,Floeth M.,Fritz C.,Gaillardin C.,Garcia-Cantalejo J.M.,Glansdorff N.,Goffeau A.,Gueldener U.,Herbert C.J.,Heumann K.,Heuss-Neitzel D.,Hilbert H.,Hinni K.,Iraqui Houssaini I.,Jacquet M.,Jimenez A.,Jonniaux J.-L.,Karpfinger-Hartl L.,Lanfranchi G.,Lepingle A.,Levesque H.,Lyck R.,Maftahi M.,Mallet L.,Maurer C.T.C.,Messenguy F.,Mewes H.-W.,Moestl D.,Nasr F.,Nicaud J.-M.,Niedenthal R.K.,Pandolfo D.,Pierard A.,Piravandi E.,Planta R.J.,Pohl T.M.,Purnelle B.,Rebischung C.,Remacha M.A.,Revuelta J.L.,Rinke M.,Saiz J.E.,Sartorello F.,Scherens B.,Sen-Gupta M.,Soler-Mira A.,Urbanus J.H.M.,Valle G.,Van Dyck L.,Verhasselt P.,Vierendeels F.,Vissers S.,Voet M.,Volckaert G.,Wach A.,Wambutt R.,Wedler H.,Zollner A.,Hani J.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
Nature
387
93-98
1997
638636
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
638637
Mishina M.,Roggenkamp R.,Schweizer E.
Yeast mutants defective in acetyl-coenzyme A carboxylase and biotin: apocarboxylase ligase.
Eur. J. Biochem.
111
79-87
1980
638638
Roggenkamp R.,Numa S.,Schweizer E.
Fatty acid-requiring mutant of Saccharomyces cerevisiae defective in acetyl-CoA carboxylase.
Proc. Natl. Acad. Sci. U.S.A.
77
1814-1817
1980
638639
Chirala S.S.
Coordinated regulation and inositol-mediated and fatty acid-mediated repression of fatty acid synthase genes in Saccharomyces cerevisiae.
Proc. Natl. Acad. Sci. U.S.A.
89
10232-10236
1992
638640
Hasslacher M.,Ivessa A.S.,Paltauf F.,Kohlwein S.D.
Acetyl-CoA carboxylase from yeast is an essential enzyme and is regulated by factors that control phospholipid metabolism.
J. Biol. Chem.
268
10946-10952
1993
638641
Vahlensieck H.F.,Pridzun L.,Reichenbach H.,Hinnen A.
Identification of the yeast ACC1 gene product (acetyl-CoA carboxylase) as the target of the polyketide fungicide soraphen A.
Curr. Genet.
25
95-100
1994
638642
Chirala S.S.,Zhong Q.,Huang W.,al-Feel W.
Analysis of FAS3/ACC regulatory region of Saccharomyces cerevisiae: identification of a functional UASINO and sequences responsible for fatty acid mediated repression.
Nucleic Acids Res.
22
412-418
1994
638643
Schneiter R.,Hitomi M.,Ivessa A.S.,Fasch E.V.,Kohlwein S.D.,Tartakoff A.M.
A yeast acetyl coenzyme A carboxylase mutant links very-long-chain fatty acid synthesis to the structure and function of the nuclear membrane-pore complex.
Mol. Cell. Biol.
16
7161-7172
1996
638644
Ivessa A.S.,Schneiter R.,Kohlwein S.D.
Yeast acetyl-CoA carboxylase is associated with the cytoplasmic surface of the endoplasmic reticulum.
Eur. J. Cell Biol.
74
399-406
1997
638645
Schneiter R.,Guerra C.E.,Lampl M.,Tatzer V.,Zellnig G.,Klein H.L.,Kohlwein S.D.
A novel cold-sensitive allele of the rate-limiting enzyme of fatty acid synthesis, acetyl coenzyme A carboxylase, affects the morphology of the yeast vacuole through acylation of Vac8p.
Mol. Cell. Biol.
20
2984-2995
2000
638646
Gao H.,Sumanaweera N.,Bailer S.M.,Stochaj U.
Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p.
J. Biol. Chem.
278
25331-25340
2003
638647
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
638648
Gruhler A.,Olsen J.V.,Mohammed S.,Mortensen P.,Faergeman N.J.,Mann M.,Jensen O.N.
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Mol. Cell. Proteomics
4
310-327
2005
638649
Li X.,Gerber S.A.,Rudner A.D.,Beausoleil S.A.,Haas W.,Villen J.,Elias J.E.,Gygi S.P.
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
J. Proteome Res.
6
1190-1197
2007
638650
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
638651
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
638652
Van Damme P.,Lasa M.,Polevoda B.,Gazquez C.,Elosegui-Artola A.,Kim D.S.,De Juan-Pardo E.,Demeyer K.,Hole K.,Larrea E.,Timmerman E.,Prieto J.,Arnesen T.,Sherman F.,Gevaert K.,Aldabe R.
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Proc. Natl. Acad. Sci. U.S.A.
109
12449-12454
2012
638653
Zhang H.,Yang Z.,Shen Y.,Tong L.
Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase.
Science
299
2064-2067
2003
638654
Shen Y.,Volrath S.L.,Weatherly S.C.,Elich T.D.,Tong L.
A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product.
Mol. Cell
16
881-891
2004
638655
Zhang H.,Tweel B.,Tong L.
Molecular basis for the inhibition of the carboxyltransferase domain of acetyl-coenzyme-A carboxylase by haloxyfop and diclofop.
Proc. Natl. Acad. Sci. U.S.A.
101
5910-5915
2004
