Sequence of TOXA_PSEAE

NAD+-diphthamide ADP-ribosyltransferase

P11439

638

69284

621604

Gray G.L.,Smith D.H.,Baldridge J.S.,Harkins R.N.,Vasil M.L.,Chen E.Y.,Heyneker H.L.

Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa.

Proc. Natl. Acad. Sci. U.S.A.

81

2645-2649

1984

621605

Stover C.K.,Pham X.-Q.T.,Erwin A.L.,Mizoguchi S.D.,Warrener P.,Hickey M.J.,Brinkman F.S.L.,Hufnagle W.O.,Kowalik D.J.,Lagrou M.,Garber R.L.,Goltry L.,Tolentino E.,Westbrock-Wadman S.,Yuan Y.,Brody L.L.,Coulter S.N.,Folger K.R.,Kas A.,Larbig K.,Lim R.M.,Smith K.A.,Spencer D.H.,Wong G.K.-S.,Wu Z.,Paulsen I.T.,Reizer J.,Saier M.H. Jr.,Hancock R.E.W.,Lory S.,Olson M.V.

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.

Nature

406

959-964

2000

621606

Carroll S.F.,Collier R.J.

Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin.

J. Biol. Chem.

262

8707-8711

1987

621607

Chaudhary V.K.,Jinno Y.,Galo M.G.,Fitzgerald D.,Pastan I.

Mutagenesis of Pseudomonas exotoxin in identification of sequences responsible for the animal toxicity.

J. Biol. Chem.

265

16306-16310

1990

621608

Bourdenet S.,Vacheron M.-J.,Guinand M.,Michel G.,Arminjon F.

Biochemical and immunochemical studies of proteolytic fragments of exotoxin A from Pseudomonas aeruginosa.

Eur. J. Biochem.

192

379-385

1990

621609

Kounnas M.Z.,Morris R.E.,Thompson M.R.,FitzGerald D.J.,Strickland D.K.,Saelinger C.B.

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A.

J. Biol. Chem.

267

12420-12423

1992

621610

McKee M.L.,FitzGerald D.J.

Reduction of furin-nicked Pseudomonas exotoxin A: an unfolding story.

Biochemistry

38

16507-16513

1999

621611

Jorgensen R.,Purdy A.E.,Fieldhouse R.J.,Kimber M.S.,Bartlett D.H.,Merrill A.R.

Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae.

J. Biol. Chem.

283

10671-10678

2008

621612

Turgeon Z.,Jorgensen R.,Visschedyk D.,Edwards P.R.,Legree S.,McGregor C.,Fieldhouse R.J.,Mangroo D.,Schapira M.,Merrill A.R.

Newly discovered and characterized antivirulence compounds inhibit bacterial mono-ADP-ribosyltransferase toxins.

Antimicrob. Agents Chemother.

55

983-991

2011

621613

Li M.,Dyda F.,Benhar I.,Pastan I.,Davies D.R.

The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin.

Proc. Natl. Acad. Sci. U.S.A.

92

9308-9312

1995

621614

Li M.,Dyda F.,Benhar I.,Pastan I.,Davies D.R.

Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation.

Proc. Natl. Acad. Sci. U.S.A.

93

6902-6906

1996

621615

Jorgensen R.,Wang Y.,Visschedyk D.,Merrill A.R.

The nature and character of the transition state for the ADP-ribosyltransferase reaction.

EMBO Rep.

9

802-809

2008