Sequence of DTX_CORBE
EC Number:2.4.2.36
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
NAD+ + diphthamide-[translation elongation factor 2] = nicotinamide + N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2]
Other sequences found for EC No. 2.4.2.36
General information:
Sequence
0 MLVRGYVVSR KLFASILIGA LLGIGAPPSA HAGADDVVDS SKSFVMENFS SYHGTKPGYV
60 DSIQKGIQKP KSGTQGNYDD DWKGFYSTDN KYDAAGYSVD NENPLSGKAG GVVKVTYPGL
120 TKVLALKVDN AETIKKELGL SLTEPLMEQV GTEEFIKRFG DGASRVVLSL PFAEGSSSVE
180 YINNWEQAKA LSVELEINFE TRGKRGQDAM YEYMAQACAG NRVRRSVGSS LSCINLDWDV
240 IRDKTKTKIE SLKEHGPIKN KMSESPNKTV SEEKAKQYLE EFHQTALEHP ELSELKTVTG
300 TNPVFAGANY AAWAVNVAQV IDSETADNLE KTTAALSILP GIGSVMGIAD GAVHHNTEEI
360 VAQSIALSSL MVAQAIPLVG ELVDIGFAAY NFVESIINLF QVVHNSYNRP AYSPGHKTQP
420 FLHDGYAVSW NTVEDSIIRT GFQGESGHDI KITAENTPLP IAGVLLPTIP GKLDVNKSKT
480 HISVNGRKIR MRCRAIDGDV TFCRPKSPVY VGNGVHANLH VAFHRSSSEK IHSNEISSDS
540 IGVLGYQKTV DHTKVNSKLS LFFEIKS
Download this sequence
in fasta formatDownload all sequences for 2.4.2.36
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
537839
Greenfield L.,Bjorn M.J.,Horn G.,Fong D.,Buck G.A.,Collier R.J.,Kaplan D.A.
Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta.
Proc. Natl. Acad. Sci. U.S.A.
80
6853-6857
1983
537840
Delange R.J.,Williams L.C.,Drazin R.E.,Collier R.J.
The amino acid sequence of fragment A, an enzymically active fragment of diphtheria toxin. III. The chymotryptic peptides, the peptides derived by cleavage at tryptophan residues, and the complete sequence of the protein.
J. Biol. Chem.
254
5838-5842
1979
537841
Michel A.,Dirkx J.
Occurrence of tryptophan in the enzymically active site of diphtheria toxin fragment A.
Biochim. Biophys. Acta
491
286-295
1977
537842
Papini E.,Santucci A.,Schiavo G.,Domenighini M.,Neri P.,Rappuoli R.,Montecucco C.
Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin.
J. Biol. Chem.
266
2494-2498
1991
537843
Tsuneoka M.,Nakayama K.,Hatsuzawa K.,Komada M.,Kitamura N.,Mekada E.
Evidence for involvement of furin in cleavage and activation of diphtheria toxin.
J. Biol. Chem.
268
26461-26465
1993
537844
Jorgensen R.,Purdy A.E.,Fieldhouse R.J.,Kimber M.S.,Bartlett D.H.,Merrill A.R.
Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae.
J. Biol. Chem.
283
10671-10678
2008
537845
Turgeon Z.,White D.,Jorgensen R.,Visschedyk D.,Fieldhouse R.J.,Mangroo D.,Merrill A.R.
Yeast as a tool for characterizing mono-ADP-ribosyltransferase toxins.
FEMS Microbiol. Lett.
300
97-106
2009
537846
Choe S.,Bennett M.J.,Fujii G.,Curmi P.M.G.,Kantardjieff K.A.,Collier R.J.,Eisenberg D.
The crystal structure of diphtheria toxin.
Nature
357
216-222
1992
537847
Bell C.E.,Eisenberg D.
Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide.
Biochemistry
35
1137-1149
1996
537848
Bell C.E.,Eisenberg D.
Crystal structure of nucleotide-free diphtheria toxin.
Biochemistry
36
481-488
1997
537849
Louie G.V.,Yang W.,Bowman M.E.,Choe S.
Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor.
Mol. Cell
1
67-78
1997
