Sequence of APX_STRGG
EC Number:3.4.11.24
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aminopeptidase S
P80561
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
445
45940
Reaction
release of an N-terminal amino acid with a preference for large hydrophobic amino-terminus residues
Other sequences found for EC No. 3.4.11.24
General information:
Sequence
0 MRPNRFSLRR SPTAVAAVAL AAVLAAGAPA AQAAGAAAPT AAAAAAPDIP LANVKAHLTQ
60 LSTIAANNGG NRAHGRPGYK ASVDYVKAKL DAAGYTTTLQ QFTSGGATGY NLIADWPGGD
120 PNKVLMAGAH LDSVSSGAGI NDNGSGSAAV LETALAVSRA GYQPDKHLRF AWWGAEELGL
180 IGSKYYVNNL PSADRSKLAG YLNFDMIGSP NPGYFVYDDD PVIEKTFKDY FAGLNVPTEI
240 ETEGDGRSDH APFKNVGVPV GGLFTGAGYT KSAAQAQKWG GTAGQAFDRC YHSSCDSLSN
300 INDTALDRNS DAAAHAIWTL SSGTGEPPTG EGVFSNTTDV AIPDAGAAVT SSVAVTGRTG
360 NAPAALQVGV DIKHTYRGDL VVDLLAPDGT AYRLKNSSSG DSADNVIATY TVNASSEVAN
420 GSWKLRVQDI ARQDTGYIDS WKLTF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
514921
Ohnishi Y.,Ishikawa J.,Hara H.,Suzuki H.,Ikenoya M.,Ikeda H.,Yamashita A.,Hattori M.,Horinouchi S.
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.
J. Bacteriol.
190
4050-4060
2008
514922
Maras B.,Greenblatt H.M.,Shoham G.,Spungin-Bialik A.,Blumberg S.,Barra D.
Aminopeptidase from Streptomyces griseus: primary structure and comparison with other zinc-containing aminopeptidases.
Eur. J. Biochem.
236
843-846
1996
514923
Spungin A.,Blumberg S.
Streptomyces griseus aminopeptidase is a calcium-activated zinc metalloprotein. Purification and properties of the enzyme.
Eur. J. Biochem.
183
471-477
1989
514924
Ben-Meir D.,Spungin A.,Ashkenazi R.,Blumberg S.
Specificity of Streptomyces griseus aminopeptidase and modulation of activity by divalent metal ion binding and substitution.
Eur. J. Biochem.
212
107-112
1993
514925
Fundoiano-Hershcovitz Y.,Rabinovitch L.,Langut Y.,Reiland V.,Shoham G.,Shoham Y.
Identification of the catalytic residues in the double-zinc aminopeptidase from Streptomyces griseus.
FEBS Lett.
571
192-196
2004
514926
Hershcovitz Y.F.,Gilboa R.,Reiland V.,Shoham G.,Shoham Y.
Catalytic mechanism of SGAP, a double-zinc aminopeptidase from Streptomyces griseus.
FEBS J.
274
3864-3876
2007
514927
Greenblatt H.M.,Almog O.,Maras B.,Spungin-Bialik A.,Barra D.,Blumberg S.,Shoham G.
Streptomyces griseus aminopeptidase: X-ray crystallographic structure at 1.75-A resolution.
J. Mol. Biol.
265
620-636
1997
514928
Reiland V.,Gilboa R.,Spungin-Bialik A.,Schomburg D.,Shoham Y.,Blumberg S.,Shoham G.
Binding of inhibitory aromatic amino acids to Streptomyces griseus aminopeptidase.
Acta Crystallogr. D
60
1738-1746
2004
