Sequence of HXK1_MOUSE
EC Number:2.7.1.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + D-glucose = ADP + D-glucose 6-phosphate
Other sequences found for EC No. 2.7.1.1
General information:
Sequence
0 MGWGAPLLSR MLHGPGQAGE TSPVPERQSG SENPASEDRR PLEKQCSHHL YTMGQNCQRG
60 QAVDVEPKIR PPLTEEKIDK YLYAMRLSDE ILIDILTRFK KEMKNGLSRD YNPTASVKML
120 PTFVRSIPDG SEKGDFIALD LGGSSFRILR VQVNHEKSQN VSMESEVYDT PENIVHGSGS
180 QLFDHVAECL GDFMEKRKIK DKKLPVGFTF SFPCRQSKID EAVLITWTKR FKASGVEGAD
240 VVKLLNKAIK KRGDYDANIV AVVNDTVGTM MTCGYDDQQC EVGLIIGTGT NACYMEELRH
300 IDLVEGDEGR MCINTEWGAF GDDGSLEDIR TEFDRELDRG SLNPGKQLFE KMVSGMYMGE
360 LVRLILVKMA KESLLFEGRI TPELLTRGKF TTSDVAAIET DKEGVQNAKE ILTRLGVEPS
420 HDDCVSVQHV CTIVSFRSAN LVAATLGAIL NRLRDNKGTP RLRTTVGVDG SLYKMHPQYS
480 RRFHKTLRRL VPDSDVRFLL SESGSGKGAA MVTAVAYRLA EQHRQIEETL SHFRLSKQAL
540 MEVKKKLRSE MEMGLRKETN SRATVKMLPS YVRSIPDGTE HGDFLALDLG GTNFRVLLVK
600 IRSGKKRTVE MHNKIYSIPL EIMQGTGDEL FDHIVSCISD FLDYMGIKGP RMPLGFTFSF
660 PCKQTSLDCG ILITWTKGFK ATDCVGHDVA TLLRDAVKRR EEFDLDVVAV VNDTVGTMMT
720 CAYEEPSCEI GLIVGTGSNA CYMEEMKNVE MVEGNQGQMC INMEWGAFGD NGCLDDIRTD
780 FDKVVDEYSL NSGKQRFEKM ISGMYLGEIV RNILIDFTKK GFLFRGQISE PLKTRGIFET
840 KFLSQIESDR LALLQVRAIL QQLGLNSTCD DSILVKTVCG VVSKRAAQLC GAGMAAVVEK
900 IRENRGLDHL NVTVGVDGTL YKLHPHFSRI MHQTVKELSP KCTVSFLLSE DGSGKGAALI
960 TAVGVRLRGD PTNA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
45735
Arora K.K.,Fanciulli M.,Pedersen P.L.
Glucose phosphorylation in tumor cells. Cloning, sequencing, and overexpression in active form of a full-length cDNA encoding a mitochondrial bindable form of hexokinase.
J. Biol. Chem.
265
6481-6488
1990
45736
Mori C.,Welch J.E.,Fulcher K.D.,O'Brien D.A.,Eddy E.M.
Unique hexokinase messenger ribonucleic acids lacking the porin-binding domain are developmentally expressed in mouse spermatogenic cells.
Biol. Reprod.
49
191-203
1993
45737
Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.
Lineage-specific biology revealed by a finished genome assembly of the mouse.
PLoS Biol.
7
0-0
2009
45739
Travis A.J.,Foster J.A.,Rosenbaum N.A.,Visconti P.E.,Gerton G.L.,Kopf G.S.,Moss S.B.
Targeting of a germ cell-specific type 1 hexokinase lacking a porin-binding domain to the mitochondria as well as to the head and fibrous sheath of murine spermatozoa.
Mol. Biol. Cell
9
263-276
1998
45740
Travis A.J.,Sui D.,Riedel K.D.,Hofmann N.R.,Moss S.B.,Wilson J.E.,Kopf G.S.
A novel NH(2)-terminal, nonhydrophobic motif targets a male germ cell-specific hexokinase to the endoplasmic reticulum and plasma membrane.
J. Biol. Chem.
274
34467-34475
1999
45741
Nakamura N.,Mori C.,Eddy E.M.
Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5.
Biol. Reprod.
82
504-515
2010
45742
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
45743
Lo J.C.,Jamsai D.,O'Connor A.E.,Borg C.,Clark B.J.,Whisstock J.C.,Field M.C.,Adams V.,Ishikawa T.,Aitken R.J.,Whittle B.,Goodnow C.C.,Ormandy C.J.,O'Bryan M.K.
RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
PLoS Genet.
8
0-0
2012
45744
Wolf A.J.,Reyes C.N.,Liang W.,Becker C.,Shimada K.,Wheeler M.L.,Cho H.C.,Popescu N.I.,Coggeshall K.M.,Arditi M.,Underhill D.M.
Hexokinase is an innate immune receptor for the detection of bacterial peptidoglycan.
Cell
166
624-636
2016
